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Online now! Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells by Alexander Sobinoff, Salvatore Di Maro, hildapickett, Sandro Cosconati, et al dlvr.it/SzrGYZ #chembiol

Take a peek at my cover art accepted for the 21 Dec issue of CellChemicalBiology! Gratitude to Fondazione AIRC per la ricerca sul cancro for supporting my research and shout-out to fellow authors hildapickett, Sadimaro, and Alex Sobinoff. #drugdiscovery #CancerResearch

Streamlining Large Chemical Library Docking with Artificial Intelligence: the PyRMD2Dock Approach #Docking #DrugDiscovery pubs.acs.org/doi/10.1021/ac… MicheleRoggia Giorgio Amendola Sadimaro Sandro Cosconati #JCIM ASAP #ApplicationNote

📣 Session 9 – Prof. Sandro COSCONATI from UniversitàVanvitelli is now on the stage for talk titled “From Reversible to Irreversible Peptide Inhibitors of the TRF2TRFH Recruiting Functions: a Strategy to Induce Replication Stress in Cancer Cells”. Stay tuned! 🔬💡 #EFMCISMC24 #MedChem

Next talk in the peptide session at #EFMCISMC24 is given by Sandro Cosconati (Sandro Cosconati), describing his strategy to induce replication stress in cancer cells, from reversible to irreversible peptide inhibitors of the TRF2TRFH recruiting functions. EFMC DCF-SCI

Discovering Dually Active Anti-cancer Compounds with a Hybrid AI-structure-based Approach JCIM & JCTC Journals 1/ In this study, a novel hybrid AI-structure-based approach was developed to identify compounds that can target both G-quadruplex (G4) structures and the poly(ADP-ribose)

Our manuscript is now featured on the front cover of JCIM & JCTC Journals! Huge thanks to the talented Benito Natale and MicheleRoggia for creating this amazing cover art! #MyACSCover ACS for Authors

Discovering Dually Active Anti-cancer Compounds with a Hybrid AI-structure-based Approach #DrugDiscovery pubs.acs.org/doi/10.1021/ac… MicheleRoggia Benito Natale Giorgio Amendola Jussara Amato Sandro Cosconati #JCIM Vol64 Issue21 #PharamceuticalModeling

On the issue 1 cover is work by Sabrina Taliani, Floriana Morgillo, Sandro Cosconati & co on the discovery of c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer, take a look⬇ pubs.rsc.org/en/content/art… 📍UniversitàVanvitelli Università di Pisa Read the full issue👉pubs.rsc.org/en/journals/jo…

ESMEC 2025 URBINO - European School of Medicinal Chemistry: June 29 – July 3, 2025 Tentative Programme Available and REGISTRATION is nor OPEN! For all the info: esmec.eu We are waiting for you in Urbino! DCF-SCI EFMC EFMC Young Scientists Network SCI Giovani

We're hiring!🚨Our lab Sydney Chemistry is looking for two new #chempostdoc for our drug discovery program: 1) Synthetic/Med Chem (small molecule hit-to-lead)🧪 usyd.wd3.myworkdayjobs.com/en-US/USYD_EXT… 2) Chemical Biology (peptide inhibitors)🦠 usyd.wd3.myworkdayjobs.com/en-US/USYD_EXT… Pls spread the word!🙏

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