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Sarah Stahl-Rommel presenting Nanopore sequencing based microbiome analysis of the international space station. So coool. #nanoporeconf

🚀🚀🚀 #NanoporeConf

PhD thesis finally submitted, woo! I can rest in peace now

We're very happy to share this study in Nucleic Acids Res, led by Mark Girasol and Emma Marie Briggs, describing R-loop interactors in T. brucei, including new functions in immune evasion. Great work, Mark, and thanks to all authors UofG Sii Centre For Parasitology rb.gy/rnu7w

We’re pleased to share a new study led by Jeziel D. Damasceno describing how R-loops and RNase H1 dictate chromosome size-dependent DNA replication timing and genome stability in Leishmania Emma Marie Briggs Marija Krasiļņikova Catarina A. Marques biorxiv.org/content/10.110…

Our new study led by Marija Krasiļņikova Catarina A. Marques We used Nanopore sequencing to map DNA replication across the whole T. brucei genome, revealing partitioning that drives instability for immune evasion Kathryn Crouch Emma Marie Briggs biorxiv.org/content/10.110…

Is 915 jupyter notebook cells an indication that it's time to move on to analysing some other data?

Funded PhD available with us, Martin Llewellyn and James Cotton UofG Sii UofG SBOHVM Centre For Parasitology to study genome replication and (in)stability across diverse kinetoplastids. Applications (via FindaPhD) taken from Nov 1st - Jan 12th. Enquiries welcome. tinyurl.com/mfz4yh3k

Very happy to share new work UofG Sii Centre For Parasitology led by Jeziel D. Damasceno describing very abundant, previously undetected DNA replication activity in Leshmania using DNAscent, a technique developed by Conrad Nieduszynski 🇺🇦 Great work, Jeziel. shorturl.at/G7uRm

How does Leishmania major replicate its genome? A sneaky Sneak Peek at a recent manuscript from our lab McCulloch Lab Group (led by Jeziel Jeziel D. Damasceno) currently under review: dx.doi.org/10.2139/ssrn.5…

Are you interested in genome maintenance, organisation and replication? We have a BBSRC-funded PhD position to use multi ‘omics’ approaches to tackle this problem! ⁦McCulloch Lab Group⁩ ⁦University of York⁩ ⁦York Biomedical Research Institute⁩ findaphd.com/phds/project/m…

Fancy a sneak peek into Leishmania’s unusual DNA replication programming? At McCulloch Lab Group we used D-Nascent to map origins & forks at the single-molecule level, revealing novel, abundant replication initiation events across its plastic genome. See links below👇

Drs Stephen Larcombe Jane Munday & Richard McCulloch highlight @MonicaMugnier & colleagues’ nature article on tissue spaces as #reservoirs of #AntigenicDiversity for #Trypanosoma #brucei. Biological Sciences | University of Edinburgh Centre For Parasitology UofG Sii Molecular Microbiology and Immunology at JHSPH Johns Hopkins Bloomberg School of Public Health #Trypanosome cell.com/trends/parasit…

DNA replication beyond the cores of megabase chromosomes of T. brucei -- some of my PhD work is FINALLY out! doi.org/10.1038/s41467… thanks to Richard McCulloch Catarina A. Marques Emma Marie Briggs Dario, Kathryn, Graham and Craig! 🥳

We're pleased to share a new paper UofG Sii Centre For Parasitology led by Marija Krasiļņikova Catarina A. Marques where we show that T. brucei DNA replication dynamics reflect structural and functional compartmentalisation of the genome. Well done Marija! doi.org/10.1038/s41467…

Excited to share our latest work on R-loops and RNAse H1, exploring their roles in genome replication timing and stability. It’s now published! nature.com/articles/s4146… McCulloch Lab Group Emma Marie Briggs Marija Krasiļņikova Catarina A. Marques

More recent work from the McCulloch lab! Check out Jeziel's Jeziel D. Damasceno recent paper on R-loops, DNA replication and genomic stability in Leishmania major nature.com/articles/s4146… in Nature Communications McCulloch Lab Group Catarina A. Marques Richard McCulloch Emma Marie Briggs

32 T2T!!! Happy to share our preprint showing the molecular karyotype of #Trypanosomacruzi Gonzalo Greif Carámbula FlorenciaDíazViraqué #MariaLChiribao Carlos Sanz PacBio HiFi biorxiv.org/content/10.110…