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Association between infectious diseases consultation and mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study ✅ Just Accepted bit.ly/4avkdoJ

🦠We call a lot of things “sepsis” 🚨In our new Annals of Int Med study, we examine how broad this grab bag really is ⚠️Among ~75,000 patients with sepsis, we found a remarkably wide spectrum of presentations & outcomes across infection source & organ dysfunction patterns Thread ⬇️

It is crucial for trials to be as relevant as possible to the populations they seek to inform, yet often trials lack diversity and fail to include a range of underserved groups. The #INCLUDE initiative is useful to help trials to address this 1/8 #MethodologyMonday #90

Just out #AACJournal ASM. HCO3 Resensitisation of MRSA to B-lactam and outcomes in the CAMERA2 trial journals.asm.org/doi/10.1128/aa… First author: Neta Petersiel In memorandam of Arnold Bayer Joshua Davis Benjamin Howden UniMelb MDHS Doherty Institute Stefano Giulieri Thread

Whether antibiotic de-escalation reduces risk of subsequent antibiotic resistance is uncertain🆕️⚡️The largest study to date BL Abx De-escalation was associated w 🔽 risk of new GN resistance development compared to no change in hospitalized pts w Sepsis academic.oup.com/cid/article/do…

Preventing new Gram-negative resistance through beta-lactam de-escalation in hospitalized patients with sepsis: A retrospective cohort study ✅ Just Accepted 🔗 bit.ly/4cdNghP

“In this cohort study of 8807 patients, we describe risk factors and clinical outcomes of patients with persistent Gram-negative bacteraemia” Read the #OpenAccess article by Sean Ong Steven Tong Brad Langford et al: doi.org/10.1093/jac/dk… OUP Medicine Oxford Journals #JACNews

🆕️⚡️⚡️Single-centre study Staphylococcus aureus bloodstream infection rates were 56% lower during the monsoonal wet season when patients on hemodialysis receive supervised melioidosis prophylaxis with trimethoprim sulfamethoxazole #idxposts academic.oup.com/ofid/article/d…

Great to see Trial Forge Guidance 4 on reporting guidance for SWATs and the EQUATOR network site (equator-network.org). Have a look at the SWAT reporting guidance is at: doi.org/10.1186/s13063…

🚨 2️⃣ PhD opportunities with us in Melbourne Centre for Antibiotic Allergy & Research Doherty Institute 👇 1️⃣ PhD examining RCT validation of clinical decision rules in antibiotic allergy - beyond #PENFAST 2️⃣ PhD examining prolonged oral challenge in #penicillinallergy - #PROSPECTOR2 study Suited to

A seven-day course of antibiotics for hospitalized patients with bloodstream infections is just as effective as a 14-day course, according to new findings presented at #IDWeek2024. Learn more: idsociety.org/news--publicat…