🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Reality check on AD biomarkers from Carole Dufouil at DPUK conf In MEMENTO, minimal variability of BBMs explained by clinical factors. And BBMs add little predictive ability beyond standard demographic/neuropsych tests What happens when outcome = people instead of PET scans!

Changing Story of the Dementia Epidemic jamanetwork.com/journals/jama/…

What is the prognostic capacity of plasma p-tau217 in cognitively unimpaired patients? Research in Alzheimer’s & Dementia reports plasma p-tau217 is a prognostic marker for identifying individuals who will develop cognitive impairment within ten years. alz-journals.onlinelibrary.wiley.com/doi/full/10.10…

This is not a good example of trustworthy science communication. And The Lancet Neurology should not have published a paper stating that the effect size was "not statistically significant but is clinically meaningful". See full response here: sciencemediacentre.org/expert-reactio…

The responsibility of health: shifting the focus from individuals to s... sciencedirect.com/science/articl…

Excellent summary of our recent study from Naaheed Mukadam and National Institute for Health and Care Research Population-level policies on risk factors for dementia could reduce costs evidence.nihr.ac.uk/alert/populati…

In this Australian (relatively affluent) sample, social support seems to mitigate SDOH relationship with dementia for men but not women. Social determinants of health and risk of dementia among older men and women: A 12‐year cohort study in Australia alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Systematic review of MCI prognosis from Simone Salemme and co, nicely showing selection bias arising from clinical samples - population-based samples show almost half the conversion rate and more than double the rate of reversion to normal cognition alz-journals.onlinelibrary.wiley.com/doi/full/10.10…

Shingles vaccination programme in Wales appears to be associated with reduction in dementia risk. Healthcare records aren't a perfect way of capturing dementia incidence but this is a potentially important finding rdcu.be/egagG

Ever heard of POPPED? It’s an innovative platform that connects researchers directly with people affected by dementia. By sharing your insights, you help shape dementia research to truly meet community needs. Check it out: popped.org.uk #DementiaCare #PublicEngagement

In this Chinese population-based sample, we found that health behaviours were more strongly linked to living longer without getting dementia, compared to APOE e4 genotype. Though we didn't see any compression of the dementia morbidity (once it occurred) doi.org/10.1002/alz.70…

Dr. Seb Walsh discusses the implications of the field’s learnings about dementia risk factors, intervention and care, highlighting public health frameworks for dementia prevention that are both cost-effective and scalable in the Caribbean.

Detection Bias in EHR-Based Research on Clinical Exposures and Dementia jamanetwork.com/journals/jaman…

In population-based study (Kungsholmen), NPVs high but PPVs for blood based biomarkers 30% for single biomarkers, 45% for combination. Median follow-up 10 years. Just can't see how screening could ever be feasible with these kinds of values nature.com/articles/s4159…

V important paper from Sarah Assad and team on external validity of cognitive assessment studies. Non-response in cognitive studies is not random - people not taking part are older, have lower cognition, and reduced functioning. Must weight analyses! alz-journals.onlinelibrary.wiley.com/doi/full/10.10…

The Limited Role of Alzheimer Disease Blood-Based Biomarkers in Primary Care jamanetwork.com/journals/jamai…

theconversation.com/do-people-real…

theconversation.com/the-roots-of-d…

Interested in how we lower the population's risk of developing #dementia? Check out the refreshed webpages of our research group, including an up to date Evidence Hub. Want to learn more? Get in touch! coghealth.net.au/population-bas…

A couple of months ago in The BMJ (I’m that far behind!). This is something we should care about. We need a medical workforce that is diverse and who can relate to patients and others in the MDT.