For anybody still interested in learning what makes proteins fold and unfold slow or fast, read our recently published work on massive rate accelerations of CI2 by targeted mutations that do not change stability

Are you excited for the upcoming IDP Gordon Research Seminar/Conference starting this weekend? We are! To get things started for the GRS we will be highlighting some of the panelists and mentors attending the GRS! Get your questions ready for the panelists and prepare to network!

First, Elizabeth Rhoades of Rhoades Lab at UPenn who will be a faculty mentor and serve on the IDP GRS Navigating the Funding Landscape panel!

Our next IDP GRS faculty mentor and "Navigating the Funding Landscape" discussion panelist is Danfeng Cai

And that's a wrap for IDP GRC 2024🍝!! Thanks to all sponsors, speakers, GRC staff, and amazing attendees for making the 2024 meeting so memorable! Special thanks to our fearless chairs TanjaMittag and Birthe B. Kragelund!

Congrats to the best poster award winndes at IDP GRC 2024🏅🍝: Lucia Alvarez (EMBL) Maria Correia Davis (Aarhus) Marcos Gil-Garcia (ETH) Atar Gilat (WIS) Charlotta Lorenz (Cornell/Zurich) Jeff Lotthammer (WashU) Adam Rubin (MIT) Min Kyung Shinn (WashU) Please RT and tag!

Returning from ⁦IDP GRC⁩ collecting droplets. Grateful for belonging to a community where both science and people matter. Thrilled to have done this with ⁦TanjaMittag⁩ and for handing over to ⁦Shahar Sukenik⁩ and ⁦xavier salvatella⁩

we made the cover!! ☺️

Check out this fascinating blend of cutting-edge structural proteomics and proteome-scale adaptation to the extreme. I am honored to have contributed to this fantastic collaboration, which provides insight into intrinsic desiccation tolerance in yeast proteins!

Big news - IDPSeminars has new hosts 🥳🎉!

It has been more than four years since Alex Holehouse and I started IDPseminars and now it is time for fresh blood and fresh ideas! We are happy to announce that Chemes Lab and jackie pelham take over as hosts!

📢 Excited to share our research with Shahar Sukenik & @mvstaller on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions regulate transcription in unique ways. doi.org/10.1101/2024.1… 🧵 Highlights:

New work from Eduardo Flores examines the relationship between disordered ensemble structure and activity in transcription. Read more here 👇