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NICE appraisal for #andexanet alfa for ICH has been terminated as AZ did not provide the relevant info i.e. company have pulled the plug on it. This means andexanet will not be available in Eng, Wal, NI for ICH. Will have to see if Scotland pull it based on recent data.

The future of treatment for people with a genetic bleeding disorder is up for debate at this free event on 27 Feb. Hosted by @HaemSocUK & The Royal Society of Medicine, find out about the innovations and technologies which will shape the future of bleeding disorder care. haemophilia.org.uk/events/events-…

RCT of FXI inhibitor Abelacimab vs Rivaroxaban in AF stopped early due to significantly less bleeding with Abelacimab. Not powered to look at thrombotic events but were 7 on Rivaroxaban and 10 and 11 on the two doses of the FXI inhibitor. Paper in NEJM

Places for our Medicine and Me event on Thursday 27 February are filling up so book now to be sure you don't miss out. It's free to attend and promises to be a fascinating look into the future of bleeding disorder care and treatment. Find out more here. haemophilia.org.uk/events/events-…

A new product for severe haemophilia A which reduces the number of treatments needed while increasing the duration of factor cover has been licensed in the UK. Find out more here. haemophilia.org.uk/efa-haemophili…

If you are a #haematologist or #physiotherapist working in #haemophilia #bleedingdisorders care in Europe and work with #nurses in the field who won't see this please share with them and ask them to complete - thank you!

In an unprecedented move, the US National Institutes of Health has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”. go.nature.com/4i2EaIb

The Infected Blood Inquiry will publish an additional Report, which will consider the timeliness and adequacy of the Government’s response on compensation. Follow this link to find out more: infectedbloodinquiry.org.uk/news/infected-…

we are recruiting!! Ads live for 2 research assistants/biobankers and a data coordinator - working on a new Ludwig Cancer - MRC WIMM joint initiative to prevent progression from early to advanced blood cancer. Joint appointment between my lab and Adam Mead. Links below!

MPN Voice news - survey for a proposed study of molecular monitoring in MPN patients. @MPNSM ⁦MPN Voice⁩ ⁦Jennifer O'Sullivan⁩ Calling all MPN patients please give us your views on this new study ! mailchi.mp/195a00b66d06/m…

Prof. Mahé Isabelle presents API-CAT at #ACC2025, published in NEJM Extended anticoagulation with reduced-dose apixaban is noninferior to full-dose for preventing recurrent VTE, with less clinically relevant bleeding 🩸in patients with cancer. nejm.org/doi/full/10.10…

Important paper: In patients with cancer and venous thrombosis, extended anticoagulation with low dose Apixaban is as good as full dose Apixaban in preventing thrombosis recurrence and is associated with less bleeding. tinyurl.com/yyfuan35

This #WorldHemophiliaDay, we’re spotlighting the overlooked history of women and hemophilia. Experts Paula James and Megan Chaigneau join the ISTH Pulse Podcast to share insights from their powerful narrative review in JTH 🎧Listen: bit.ly/3Ept29w #WHD2025

Today marks World Haemophilia Day with this year’s theme being ‘Access for all: women and girls bleed too’. A huge part of our work this year is going to be focused on women and girls as we look to highlight the shortcomings in care and treatment and push for genuine change.

Monitoring ultralong half-life recombinant factor #VIII : a product-specific calibrator is urgently needed to enable accurate #measurement in all patients jthjournal.org/article/S1538-…

ISTH -- Point-of-care #ultrasound Use in Hemophilia Care. Please participate in this survey if you are interested in joint health in #Hemophilia redcap.isth.org/surveys/?s=9NY…

🎧The latest episode of Don't Just Read the Abstract podcast. Pip Nicolson and Dr Susie Shapiro discuss the implications of the recent UK #NHS approval of efanesoctocog alfa.

Thanks Pip Nicolson for a lovely welcome experience to your podcast, and sorry you couldn't join us Richard Buka 💙 to keep us on track! Amazing to see the preparation and effort that goes in to these - great work both of you!