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“we prefer not to look for shit receptors”

Join us in congratulating Shu-ou Shan of Caltech, winner of the 2024 NAS Award in Molecular Biology for her novel research on molecular mechanisms underlying critical cellular processes. Read about her important work: bit.ly/molecular-biol… #NASaward #MolecularBiology

𝗪𝗲𝗶 𝗬𝗶 𝗶𝘀 𝘁𝗵𝗲 𝘄𝗶𝗻𝗻𝗲𝗿 𝗼𝗳 𝘁𝗵𝗲 𝟮𝟬𝟮𝟰 𝗧𝗮𝘁𝗮 𝗦𝘁𝗲𝗲𝗹 𝗖𝗵𝗲𝘀𝘀 𝗧𝗼𝘂𝗿𝗻𝗮𝗺𝗲𝗻𝘁! 🏆 Wei Yi beat Abdusattorov and Gukesh in the tiebreaks, to clinch his 1st victory in the Wimbledon of Chess! Congratulations, Wei Yi. 💙 #TataSteelChess

One of my favourite letters, insightful & humane, from Richard Feynman to a former student who was having a rough time I was reflecting on it as an argument in favour of scope insensitivity, or even in favour of smaller problems:

New Huang lab publication. This time, we present "a nanopore based fruit 🍐🍊🍌🍉🍇🍈🍑ninja🥷🥷🥷" link to the paper: rdcu.be/dAu7i

Ever need a gravity column to run faster? Don’t have a syringe that fits? I’ve got a solution for you….

💡 FRETpredict is published 💡 We developed code to enable easy calculation of FRET efficiencies from large conformational ensembles using rotamer libraries for many common linker-dye pairs. 📜 doi.org/10.1038/s42003… 💾 github.com/KULL-Centre/_2… 🖥️ github.com/KULL-Centre/FR…

The 96-well western blot

Do you really need to spread plasmid libraries on mountains of plates to get uniform growth, or can you just dump them in a flask and call it a day? We make huge plasmid libraries in the de Boer Lab, so we tested whether culture method really matters. 1/ biorxiv.org/content/10.110…

Excited to introduce EMSuite Server! Our cryo-EM structure modeling and validation tools are now easily accessible on this web server: em.kiharalab.org. Includes DeepMainmast, CryoREAD, DAQ, DiffModeler, and more! If a job fails, we provide feedback within 24 hours.

"A random half of panelists were shown a CV and only a one-paragraph summary of the proposed research, while the other half were shown a CV and a full proposal. We find that withholding proposal texts from panelists did not detectibly impact rankings." link.springer.com/article/10.100…

roger federer on letting go and overcoming hard moments

So, it turns out that we now can do Western blot from single cells. Cool ! At least it worked for them in #cancer cells. Full story Nature Communications nature.com/articles/s4146…

Looking to learn everything we know about the structure and function of the GATOR1 complex? Look no further! Kuang Shen pubmed.ncbi.nlm.nih.gov/38963491/

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

Early morning celebration.

Molecular Medicine UMass Molecular Medicine at UMass Chan Medical School UMass Chan Medical School Morningside Graduate School of Biomedical Sciences celebrates Victor Ambros, our new Nobel Prize Laureate

Honoring my postdoc advisor, Steve Doxsey, who shaped my career & inspired me to explore science with creativity. A champion, artist at heart, & fearless explorer (he climbed the Golden Gate Bridge!). Cheers Steve, you will be missed. 📰 Obituary: mercadantefuneral.com/obituaries/ste…

More than 500 people, including about 60 from UMass Chan Medical School, gathered in Boston today to protest the Trump administration’s funding cuts to scientific research. The protest is nationwide. Read the The Boston Globe’s story: direc.to/mF3M #StandUpForScience RNA Therapeutics Institute

With Katerina Rohlenova pleased to announce the 2026 Prague Metabolism and Signaling Meeting (June 24-27). Two Keynotes (Vousden & Hall) and 30+ speakers in metabolism, mitochondria, aging, mTOR, & more. Please RT. Info, registration, & student discounts at: praguemetabolismsymposium.com