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Our new paper is finally out! We discovered that the human tumor suppressor protein Pdcd4 binds to the #mRNA entry channel in the 40S ribosomal subunit, where it blocks the eIF4F-independent role of eIF4A. #ribosome #CryoEM UMich RNA Center 〽️🧬 UMLifeSciences nature.com/articles/s4146…

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea biorxiv.org/cgi/content/sh… #biorxiv_cellbio

Excited to share that our SMCVdb providing detailed toxicity data on small molecules, is now published in DATABASE - The Journal of Biological Databases and Curation! Check it out here: academic.oup.com/database/artic… #Bioinformatics #DrugDiscovery #Toxicology #Database RCB

Collaborative work of slavica pavlovic djuranovic, Yaser Hashem, Jovanovic Lab and Sergej Djuranovic - a new method to isolate ribosomes and translational material in minutes. We show multiple usage of our RAPPL method in biochemical and structural assays with ribosomes. Please be free to contact

Remember, I said 5ml bacterial cultures for the isolation of ribosomes. Well, I was wrong you need 1ml culture at 0.3 -0.5 absorbance at OD600nm for this "Ribosome and RNA mini prep". Pretty good for CryoEM or any biochemical tests. Here in these figures are ribosomes purified in

Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8

Actinobacteria appear to possess a species-specific ribosome hibernation factor, found in Mycobacteria, that binds to the nascent tunnel of dormant ribosomes. More in this exciting study by Ojha and Agrawal lab: biorxiv.org/content/10.110…

Welcome and congratulations to the eleven group leaders from India, Singapore, Taiwan and Uganda who join the EMBO Global Investigator Network! Read more: embo.org/press-releases… #lifesciences

Congratulations Prem Kaushal and Rajender Motiani

We are pleased to share the press release about Dr. Motiani & Dr. Kaushal’s selection to the prestigious EMBO Global Investigation Network. pib.gov.in/PressReleseDet… Department of Biotechnology Dr Jitendra Singh EMBO YIP Prem Kaushal Rajender Motiani Rajesh Gokhale UNESCO 🏛️ #Education #Sciences #Culture 🇺🇳

✨#RCBOpenDay2025 ✨ Visit us on this National Science Day to get immersed in the exciting research of RCB! Register your school/college here - bit.ly/RCBOpenDay Visit but.ly/RCBSciSkit to know more about nukkad natak competition. #NationalScienceDay #RCBResearch

New paper from the lab in Nucleic Acids Res in which the structure of MutL-CTD- processivity complex provides insight regarding strand discrimination in methyl-independent mismatch repair academic.oup.com/nar/article/53…

Science hits the Streets! Young minds raise awareness through engaging Nukkad Natak performances on critical issues including pollution, sustainable cities, and pandemic management during #NationalScienceDay celebration at RCB. #ScienceCommunication Dr Jitendra Singh

RCB Science Club Our students at RCB published science magazine on Science Day. Such a wonderful effort

The origins and evolution of translation factors dlvr.it/TJkyL8

A drug approved to treat migraine headaches can also alleviate debilitating non-headache symptoms, such as fatigue, brain fog and blinding light sensitivity go.nature.com/3RWbzc2

2 of 2: Instead of activating a water molecule for hydrolysis, as previously thought, release factors induce a structural change in the transfer RNA, enabling its own 2’OH group to attack and break the bond, a universal process in all organisms. science.org/doi/10.1126/sc…

Happy to share recent publication from our lab in Nature communications.