Immune vulnerabilities of mutant KRAS in pancreatic cancer Trends in Cancer doi.org/10.1016/j.trec… 👉RAS inhibitors may ameliorate RAS-induced immunosuppression -> IO combinations 👉mKRAS is immunogenic -> TCR T cells, vaccines.. 🧐opportunities for ‘drugging KRAS’ 👏excellent

Very excited to present insights in CAF heterogeneity and functionality in CCA at #TLM23, thank you to Daniela Sia and Yujin Hoshida for the invitation! Expanding network and knowledge in a collaborative environment to keep growing 💪happy to see old and new friends here!

131 new research grants means 131 new approaches to find answers that help save lives from cancer! We are proud to support this OUTSTANDING group of new grantees including Dr. Edna Cukierman, Ph.D., recipient of the American Cancer Society-Wilmott Family Professorship in #PancreaticCancer Research

Second annual Liver Cancer Shark Tank was once again standing room only. Congrats to all the presenters on the great pitches and to the winner Andrew Moon! Was fun to be a shark. #TLM2023 Amit G Singal Davide Povero, PhD, MBA @NDP1001 Daniela Sia

📢 Don't forget to tune today @ 18:00 CET for the #EASLStudio scheduled in honour of the #WorldCCADay! 📺easl.eu/easl-studio-ep… 🗣️Thomas Berg, Katie Kelley, Daniela Sia & Juan Valle #livertwitter EASLnews

#EASLStudio: 👉Check regularly the treatment response 👉 Immune check point inhibitors ➡️ have limited effect alone 👉 Do biopsy as much as possible 👉 Molecular profiling (DNA+RNA seq) for fusion & liquid biopsy for mutation identification 🧐 % of 5-yrs survival remains low

Today is World Cholangiocarcinoma Day! #WorldCCADay. Please join us in spreading awareness of CCA and sign the pledge. It's time to #BeClearOnCCA.

We are looking for a post-doctoral fellow to join our research group at Mount Sinai in New York City. Required experience with mice, friendly and teamworker. To apply: nature.com/naturecareers/…

Seeking a motivated post-doc to study novel mouse models of cholangiocarcinoma with KRASG12D mutations. Help us explore how KRAS impacts the immune response and therapy outcomes. Apply now: bit.ly/3vG5zg6 #CancerResearch #PostDocJobs #NYC #WeFindAWay Mount Sinai Department of Medicine

The Genetic and Epigenetic Drivers of CCA session at Cholangiocarcinoma Foundation was a great session with a lively discussion covering: 👉🏼 cancer epigenomics at the single cell level 👉🏼 germine genetics and CCA risk 👉🏼 genetics of CCA subtypes 👉🏼 tumor genotype-immune phenotype relationship

Grateful to the scientific community, Stacie Lindsey, Juan Valle, and a wonderful co-chair Daniela Sia for making the first Basic Science Track at Cholangiocarcinoma Foundation Annual Conference a huge success. We had remarkable speakers from all over the world in a packed room with robust discussion.

Proud of this amazing scientist @emilybramel and thankful to the Cholangiocarcinoma Foundation for another wonderful annual conference!!

On June 1, 2024, we proudly joined the Liver Life Walk NYC with 34 teams and 294 walkers. Huge thanks to Dr. Douglas Dieterich, this year's Medical Chair. Grateful to everyone who participated and supported us. #LiverLifeWalk #Gratitude #ALF Mount Sinai Department of Medicine American Liver Foundation National

Struggling to balance your research with the fast-paced world of social media? You're not alone. Join Sarah Cappuyns at #ILCA24 for our dedicated session to learn the advantages and challenges of using social media in your scientific research. 👀 ilcalive.org/annual-confere…

Our review on "Morphomolecular pathology and Genomic Insights into the Cells of Origin of Cholangiocarcinoma and combined Hepatocellular-Cholangiocarcinoma" was recently released in Am J Pathol Daniela Sia ajp.amjpathol.org/article/S0002-…

What a start for #ILCA24 ! Enthusiastic participation to the roundtables organised by the Young ILCA committee - so enlightening to hear the career development advice of our stellar speakers! Marina Baretti Grainne O'Kane chiara braconi Valerie Chew ILCA

Why we do what we do ILCA ➡️power of the patient voice from the wonderful Melinda Bachini 💕pay it forward💕 ➡️need drug & clinical trial access ➡️PROs in studies ➡️more practical trial design Cholangiocarcinoma Foundation UCD Cancer Trials CancerTrialsIreland 🌈 #ILCA24

Fantastic roundtable discussions with the experts & Young Investigators! #ILCA2024 Valerie Chew Daniela Sia chiara braconi Grainne O'Kane ILCA. Look forward to the YI masterclass today on social media & science 🧬👩‍💻Sarah Cappuyns Antonio D'Alessio

Concordance of ctDNA and tissue genomic profiling in biliary tract cancer Journal of Hepatology doi.org/10.1016/j.jhep… 👉concordance in 84.8%, 👉ctDNA revealed 🎯GA in 34.3% 👉high VAF in ctDNA associated w/ poor prognosis 🧐LB valuable option ESMO - Eur. Oncology EASL Education ILCA Cholangiocarcinoma Foundation