iReceptor Gateway (gateway.ireceptor.org) is thrilled to announce the release of iReceptor v4.0. v4.0 is a full implementation of airr_community v1.4 #AIRRseq specification, bringing new #SingleCell capabilities to the #AIRRDataCommons. Details are here: ireceptor.org/ireceptor-4

BEYOND EXCITED to share that our tonsil atlas has been published in Immunity !!! Lots of cool results and puzzlng observation that came out from the old and new analysis, which I'll try to distill in dedicated threads during the next weeks🤓 cell.com/immunity/fullt…

📢New paper out in Immunity! 🧬An atlas of cells in the human tonsil 📰The study, co-led by #CNAG and IDIBAPS, provides the most comprehensive cellular map to date, key to understand the immune system and diseases such as leukaemias and lymphomas 🔗cnag.eu/news/cellular-…

👩‍🔬We join the International Day of Women and Girls in Science: #science does not understand genders! 🙌At #CNAG, the 52% of our teams are women 🚀Let's make girls' dreams of becoming scientists come true #11F #WomenInScience #11F2024 #DiaDonaiNenaenCiència

💥Amígdaland, el #cómic que da vida a nuestro estudio del atlas celular de la amígdala 🦠Descubre cómo funciona el órgano del sistema inmunitario a través de un súper héroe: una célula B que combate los patógenos ℹ️cnag.eu/news/cellular-… #ciencia #ICTS #ICTSNews #divulgación

escape: Easy single cell analysis platform for enrichment has gotten a major overhaul. Users can now seamlessly use GSVA, ssGSEA, UCell (Santiago Carmona 🧬 🖥️ carmonation.bsky.social) and AUCell. All from within Seurat or Bioconductor workflows Vignette: borch.dev/uploads/screpe… Code: github.com/ncborcherding/…

🟣#8M | Internacional Women's Day 🧬At #CNAG, the 5⃣2⃣% of our teams are women 🙌More than 6⃣0⃣ highly talented and committed professionals, so proud of each one of them! #WomensDay2024 #DiadelaDona #DiaDeLaMujer #DiaInternacionalDeLaMujer #8MarchInternationalWomensDay #8M2024

The Tail & Tango of Cancer genome-- we developed a tool “DOME” to tame the tail of rare mutations; in another study, we describe the first chromosomal tango “Chr 11/5 fusion” in oral cancer genome. Thanks to ACTREC-TMC,Cancer Research Institute - ACTREC,Department of Biotechnology,DBT/WT India Alliance,DAE India,University of Delhi

The first project you do in your PhD is always dear to you the most! It's out in NAR Cancer (Bill Dynan - NAR Cancer Editor)! A computational method to identify cancer driving mutations using protein structure and sequence conservation. Amit Dutt Cancer Research Institute - ACTREC ACTREC-TMC

Trex accepted for publication! We used single-cell TCR embeddings + RNA to infer antigen specificity and confirmed 5 of 5 predictions!

Wanna do standard 3’, 5’ etc ⁦⁦10x Genomics⁩ applications-seq without stress? No worries! FixNCut it baby! Laura Jiménez Gracia YOU are the best! Holger Heyn Dr. Jasmine Plummer 👩🏻‍🔬🧬🇨🇦🇺🇸 CNAG ⁦Omniscope⁩ genomebiology.biomedcentral.com/articles/10.11…

Grateful to Hon’ble President of India for her blessings & encouragement to Tata Memorial Hospital ACTREC-TMC , our patients & staff! We pledge to continue serving our nation and work towards #AtmanirbharBharat #ViksitBharat

As my lab develops Seurat, I wanted to share some thoughts on the important Seurat and scanpy package selection preprint from Joseph Rich/Lior Pachter 🧵

Exciting news for the Python Single-Cell Community! Save the date for the first scverse conference in Munich from September 10-12. Inspiring talks, interactive workshops, and networking opportunities. Stay tuned for the registrations, speaker announcements, and more! #scverse2024

Amazing 3rd edition of ISCO just launching in Barcelona!!!! What a lineup!!! First session chaired by Elisabetta Mereu 🇺🇦 is 🔥🔥🔥

📢Our lab at the Josep Carreras Leukaemia Research Institute (IJC) is looking for candidates for the competitive PhD INPhINIT incoming fellowship from La Caixa Foundation. We work on the application of #singlecell genomics and ML to improve cell-based immunotherapy in Myeloma and others B-cell neoplasms. Plz RT!🔁

Our multimodal model to combine TCR sequences with scRNA-seq is finally out. The most interesting part for me was observing a clear case where the combination of TCR sequence and cell state (RNA) preserved both clonotype and cell type information, leading to a more holistic cell

Interested in deep learning and adaptive immune receptor sequences? immApex is a new R package that is a toolkit for making amino or nucleotide-sequence based models in R/Keras. Check out the beta!! repo: github.com/ncborcherding/… vignette: borch.dev/uploads/screpe…

OUT NOW! Single-cell sequencing to profile immune responses in leptomeningeal disease via #CSF #liquidbiopsy. Huge congrats Paula Nieto Juan C. Nieto Pia Zeiner CNAG Omniscope

Interested in single cell genomics but need help getting started? Check out my lab's Single Cell Genomics Day on April 25. Talks will feature recent exciting computational and experimental advances and will be live-streamed at satijalab.org/scgd. Please RT/spread the word!