Thank you Alexandre Dumoulin @axonsalex.bsky.social , this movie is mind blowing! We are immensely proud that, thanks to you, our SPY555-FastAct actin probe is represented at the Nikon Small World in Motion competition! We'll keep our fingers crossed for the competition 🤞

Super resolution imaging of mitochondria using PKMito Orange allows for visualization of cristae in real time.

We are thrilled to continue our great collaboration with Zhixing Chen and GenVivo Biotech. New products will be launched soon!

I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in Science Magazine ! (link at end of 🧵)

The MOSAIC reconfigurable microscope by Eric Betzig et al is finally out! MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics: biorxiv.org/content/10.110…

In case you haven't (yet) found a good reason to use our halotag ligands, we strongly suggest reading this great piece from the Johnsson lab! Congrats to Yin-Hsi LIN and all the co-authors.

Dear Yeast friends: Did you know PKmito ORANGE labels very nicely yeast cells mitochondria! The image appeared in a recent article by Freddy Benning : doi.org/10.1002/pro.70… PKmito ORANGE is a gentle probe with: ✅Fast staining ✅Reduced phototoxicity ✅Robust and specific mito

Our mechanosensitive Flipper-TR™ probes at work in a stunning article by Z. Chen Et al. from UWA. The study unveils a PM-ER mechanotransduction mechanism in response to external strain that dose-dependently regulates cellular metabolism. doi.org/10.1126/sciadv…

Amazing Kinase activity intergators (Kinprola) posted by Johnsson lab on BioRxiv. If you are looking for the best Halotag substrate match for Kinprola: CPY-CA it is available at Spirochrome! spirochrome.com/product/cpy-ca/

The first UK Peroxisome Network Meeting in Exeter was a great success! We're grateful to the organizers for giving us the opportunity to support this great event, especially Dr. Ruth Carmichael for coordinating with us. Triana Amen presented her amazing work on the development

PKmem probes for gentle membrane imaging are now published in PNAS! Congratulations for these exceptional probes. Available at Spirochrome!

Check it out at PNAS today. Thank you Alexandre for the collaboration!! PK Mem probes offer long time-lapse imaging of cell membrane dynamics. Made possible by Jing Ling, Yitong Liu, and all the collaborators! Available Spirochrome

🌑Goodbye bleaching, hello brightness! ☀️ We're thrilled to introduce two new ChloroAlkane (CA) ligands for Halotag labeling and featuring Zhixing Chen fantastic photoresistant BD-dyes! ✅ Highly photoresistant, no photoblueing ✅ Outstanding brightness ✅ Cell permeable ✅