Shaheen Sikandar
@ssikandar
Assistant Professor @UCSC @UCSCScience by way of @CellStanford @UCIrvine, Breast Cancer, Metastasis, Stem Cells, Science Mom!
ID: 110646399
http://www.sikandarlab.com 02-02-2010 08:18:14
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357 Followers
327 Following
Great new work from Anthony in the lab! Continues our journey on sex differences in cancer, and now extends it to platelets! No nucleus (platelets) - still a problem in cancer - grateful to Scott Cameron 🏴🇺🇸🫀🩺📟🔬🧫🧬🥋 and all our collaborators on helping us make this happen!
Excited to share our CITE-seq atlas of the aging human immune system across tissues. Great collaboration with Donna Farber, Yosef Lab, Teichlab, Jo Jones Cambridge University and partnership with CZI Science! nature.com/articles/s4159…
Our new review in Trends in Cell Biology : "The Wnt–NAD⁺ axis in cancer, aging, and tissue regeneration" cell.com/trends/cell-bi… 👏 Kudos Lamprecht & Abu Sanad and 🙏 Anjali Kusumbe Apologies to colleagues not cited (journal limits) + 🙏 to colleagues, reviewers & editor.
Congratulations Andrew Olander , who received his NIH/NCI F31 fellowship to study how early pregnancy affects the aging of mammary epithelial cells! Earlier this year, it felt like the odds were against us, but it finally came in! 🍾 #BreastCancer #aging #stemcells
Excited to share our latest study in CELL MD Anderson Cancer Center a new single cell DNA&RNA co-assay technology (wellDR-seq) used to study the interactions of DNA copy number and gene expression during breast cancer progression led by Kaile Wang Rui Ye cell.com/cell/abstract/…
1/11 In Science Magazine: A new perspective on how our intestines renew. Cells are not “pushed out” by crowding or die from apoptosis. Instead, cells play a mechanical tug-of-war, where weaker cells extrude, reframing gut renewal as force-regulated. science.org/doi/10.1126/sc…
Congratulations to the team on all their hard work on developing this first of its kind model! Dan Lester Andrea Ventura Ewan St. John Smith Walid Khaled Shelley Buffenstein Kenneth Y. Tsai Elsa Renee Flores Cancer Discovery
Can we root out the seeds of metastasis? Huiping Liu & team Northwestern Feinberg School of Medicine identify a rare T cell subset that cluster circulating tumor cells to promote metastasis in breast cancer, then provide a proof-of-concept block using VLA-4 antibody in preclinical models:
Excited to introduce our Cell Reports Medicine Cell Reports Medicine Cell Press article with the features of overextended #healthy #lifespan vs common #chronological #time: The story of a record-breaking #supercentenarian in a world burdened by #aging-related diseases.
Check out our recent study showing how to re-activate estrogen responses in originally hormone low/negative breast cancer cells! Shoutout to the amazing Deeptiman Chatterjee (He/Him) Michael Ciccone Dhivyaa Anandan! nature.com/articles/s4146…