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Human microglial cells as a therapeutic target in a neurodevelopmental disease model hubs.li/Q03gkGS_0 Collection highlight from StemCellReports Pinar Mesci, PhD et al. Martin Pera

Feeder-free culture of human pluripotent stem cells drives MDM4-mediated gain of chromosome 1q hubs.li/Q03gkHCg0 Insigneo Institute Neuroscience Institute The University of Sheffield Collection highlight from StemCellReports Martin Pera

Online Now: Functional genomic study reveals the crucial role of MIXL1 for hiPSC differentiation to definitive endoderm bit.ly/4jOUJrr ISSCR Cell Press Gairdner Foundation The Hospital for Sick Children (SickKids) CMRI Sydney Health

New research shows #exercise promotes neural graft plasticity and increases functional recovery of motor deficits in a rodent model of #Parkinsons. #dopamine #neuralplasticity bit.ly/3Gog0cV ISSCR Cell Press Gairdner Foundation The Hospital for Sick Children (SickKids) The Florey University of Sydney

New study from McGill University: #hypoxia prevents #differentiation of human trophoblast #stemcells & genes negatively regulated by low oxygen are often positively regulated by the transcription factor GCM1. #placenta #cytotrophoblast bit.ly/3GnBCX0 ISSCR Cell Press

Identifying strategies that enable effective public dialogue on human embryo research - offering insights to improve the design & delivery of engagement exercises related to complex & sensitive topics cell.com/stem-cell-repo… Babraham Institute Cambridge Sociology Loke Centre for Trophoblast Research ISSCR

New study from @mayoclinic uses #stemcells to model diabetic alpha cell dysfunction. SC-α cells mimic glucagon hypersecretion and sunitinib (tyrosine kinase inhibitor) protects against ER stress-induced dysfunction ow.ly/CWmV50VPsVt ISSCR Gairdner Foundation The Hospital for Sick Children (SickKids)

Online Now: Applying #CRISPR activation to verify single-/dual-reporter hPSC lines, dTAG #knockins & silent gene #knockouts. A rapid, effective assay without the need for differentiation to induce target gene expression. ow.ly/pVtA50VPtow Memorial Sloan Kettering Cancer Center ISSCR

Get expert guidance on submitting your research to Stem Cell Reports. Associate Editor Martin Pera shares 6️⃣ tips to navigate the submission process and effectively share your research with the world. Watch now 👉 youtu.be/xH5OMEvYw2Y Martin Pera

New scRNA-seq #regeneration study reveals two proliferating cell types in necrotic #liver injury: one dedifferentiates near necrosis & is highly proliferative; the other remains differentiated while dividing. ow.ly/fEw750VPtzH ISSCR Gairdner Foundation The Hospital for Sick Children (SickKids)

The latest podcast has dropped. Check out Clare Parish and Niamh Moriarty from The Florey talking about their latest publication in stem cell reports, tinyurl.com/y6eu29xh. Listen here tinyurl.com/yrksvxay or wherever you get your podcasts. ISSCR

The latest issue is now online tinyurl.com/56frdnzk. Check out the cover issue from the Benvenisty lab Hebrew University and Gunapala lab University of Basel on the large-scale analysis of loss of chromosome Y in human pluripotent stem cells. ISSCR

The Stem Cell Reports Best Of 2024-2025 issue is out now! Read the full issue to explore the most notable papers published over the last year. ow.ly/8ZaZ50VWsCa ISSCR Cell Press Gairdner Foundation The Hospital for Sick Children (SickKids)

Hear from Stem Cell Reports Editor-in-Chief Janet Rossant and Associate Editor Martin Pera about the countless opportunities the journal offers to amplify your research within the stem cell community. Learn how to publish your research 👉 youtube.com/watch?v=q29Fur… Martin Pera

Online now: Review explores the latest advancements in #neural #stemcell therapy for #stroke, highlighting research in #brain repair mechanisms. ow.ly/TiZr50W18Nk Institute for Regenerative Medicine Keck School of Medicine of USC ISSCR Cell Press Gairdner Foundation The Hospital for Sick Children (SickKids)

New study shows cell competition eliminates #aneuploid human pluripotent #stem cells in diploid-aneuploid mosaic populations. #MYC and #p53 levels determine competitive ability of hPSCs. ow.ly/eiuu50W19as Geisel School of Medicine at Dartmouth ISSCR Cell Press Gairdner Foundation The Hospital for Sick Children (SickKids)

New research from UCSF School of Medicine & Yale School of Medicine characterizes mouse beige #adipose depot showing conserved features with human supraclavicular brown adipose tissue, providing a preclinical model of human beige adipose tissue development and maintenance ow.ly/ilBo50W19rm ISSCR

Using #neuroectoderm #organoids derived from mouse embryonic #stem cells, this study shows a zinc finger-dependent role for #PRDM13 in regulating retinal progenitor cell fate through #WNT signaling. ow.ly/l5EH50W1a1F U-M Kellogg Eye Center University of Michigan ISSCR