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The STEPCARE trial is registered at ClinicalTrials.gov! Read more about the SEDCARE, TEMPCARE and MAPCARE at clinicaltrials.gov/ct2/show/NCT05…

stepcare.org/paolo-pelosi It is with great sadness and with the warmest memories we remember our friend and fellow researcher Professor Paolo Pelosi. Paolo was an essential member of the TTM-trial group from its start more than 15 years ago.

#CCR23: In the TAME trial involving patients with coma after out-of-hospital cardiac arrest, a strategy targeting mild hypercapnia for 24 hours did not improve neurologic outcomes at 6 months as compared with targeted normocapnia. nej.md/3p0Dsop

#TAMEtrial just published! 🩸 Does mild hypercapnia (50-55 mmHg) vs normocapnia (35-45 mmHg) improve outcomes in OHCAs admitted to the ICU? 🧠 Good neuro outcome at 6 mo: 43.5% (hypercapnia) vs 44.6% (normocapnia) 🔗 NEJM nejm.org/doi/full/10.10… #CCR23 #ResusTwitter #FOAMcc