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Researchers report in Science that infected bacteria surprisingly fight back with “hidden” genes that halt cell growth, slowing viral spread. The results highlight the potential for other “hidden” genes to be unearthed in different biological contexts. scim.ag/7Yy

Congratulations to Srinivas Viswanathan and all authors on their new study, which uncovers a genetic basis for sex differences in tRCC!

Thanks to Ilya Osterman and Sorek Lab for beautifully highlighting our recent paper! And congratulations to Max Wilkinson and Feng Zhang on their paper, which nicely agrees with and complements our findings.

Thrilled, and also in a bit of disbelief, to see our paper featured on the cover of Science Magazine! "Finding Neo" wasn't easy, but we just kept swimming (read: stared at a sequence of DNA) until the Eureka moment hit.

Today in Science Magazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with Sternberg Lab. 1/13 drive.google.com/file/d/1I-UbCR…

New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang! We uncover an unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: tinyurl.com/mr3fd493

Thrilled to share the latest work from my PhD in the bizarMD group! This has been a dream MD/PhD project, culminating in data that has already enabled access to precision therapy for a patient. Tweetorial below:

This work is now published with Science Advances with some new and exciting results. Please check out: science.org/doi/10.1126/sc…