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This order is an unmitigated disaster for US academia and for the country. It will have a chilling effect on the ability of the US to attract the world's best scientists and engineers even if lifted by a new administration because of the uncertainty it creates.

[2/2] ..., do we need to show up for the in-person sessions? 4) Do "Specicial Studies" & "Thesis Research" count towards in-person classes? 5) Actions from Johns Hopkins Epidemiology JHU OIS to fight against this rule? Actions to support international students who are on F visas?

Kicking international students out of the US during a global pandemic because their colleges are moving classes online for physical distancing hurts students. It’s senseless, cruel, and xenophobic. U.S. Immigration and Customs Enforcement and Homeland Security must drop this policy immediately. nbcnews.com/politics/immig…

We abhor the ICE decision related to F-1 visas. We remain committed to fully supporting the many Johns Hopkins Bloomberg School of Public Health students who may be impacted by these changes. We are working quickly and in collaboration across Johns Hopkins University to understand, address and oppose the announced rules.

Thanks our school Johns Hopkins University and our department jhubiostat for all the support to fight against #StudentBan. The actions and voice are encouraging for international students.

A nice thread using spline examples to explain the phenomenon in ML that the testing error can still decrease when the model complexity increases beyond the "sweet spot".

Glad to announce this as my 1st tweet - our recent benchmark study of 18 single-cell RNA-seq imputation methods genomebiology.biomedcentral.com/articles/10.11…

#postdoc #Recruiting Dr. Zhicheng Ji at Duke Biostatistics & Bioinformatics is recruiting a postdoctoral fellow to develop methods for single-cell multi-omics data analysis and integration. Contact: [email protected] Welcome to apply now careers.duke.edu/job/Durham-POS…

Big news from Pfizer, with apparent high efficacy (>90%) based on 94 confirmed COVID-19 cases at their interim analysis. A thread on how I interpret this news. Briefly: "Celebrate, but let the process play out over time as intended." 1/8 pfizer.com/news/press-rel…

Our new bioRxiv out led by Dario Righelli Lukas Weber @CrowellHL describing #SpatialExperiment Bioconductor 📦 to store, access and work with spatially resolved transcriptomics data (spot- & molecule-based) in #rstats!

Congratulations to @jtleek, winner of the COPSS Presidents' Award!!

Ni Zhao wanted to work toward improving human health and well-being, yet she was also fascinated by the beauty of math. Now, as an assistant professor of biostatistics she participates in frontline research. #STEMwomen #womenshistorymonth magazine.amstat.org/blog/2022/03/0…

Got an RNA-seq dataset with 50, 100, 200+ samples? Plug it into a differential expression tool and hope for the best? No! You need to consider QC, EDA, and modeling technical variation, or else risk generating spurious results. A thread on papers, methods, and best practices:

another blog post after a long time: marker gene selection using logistic regression and regularization for scRNAseq divingintogeneticsandgenomics.rbind.io/post/marker-ge… #scRNAseq #regression #tidymodes #rstats

Elated to announce that four new highly talented faculty will be joining Columbia University Biostatistics over the next few months. Looking forward to welcoming them soon! Wenpin Hou Xiao Wu ColumbiaPublicHealth

I learnt a ton about everything related to #scrnaseq from Twitter. However, this site is not made to preserve the pearls of knowledge exchanged among the experts. Thus, I created a blog, Single-Cell Updates (scup), to keep track of the threads! 1st post: scup.netlify.app/posts/2022-w40/

PRECAST - a data integration method for integrating multiple spatial transcriptomics datasets by aligning shared embeddings of biological effects while accounting for batch effects. nature.com/articles/s4146…

Promising approach for simulating realistic #microbiome data! Better recapitulates real data. From my former student Ni Zhao at jhubiostat and folx at Emory Public Health. MIDAS: a fast and simple simulator for realistic microbiome data biorxiv.org/content/10.110…

Only a matter of time before a paper formalized this exercise: Automated #scRNAseq cell type annotation with GPT4, evaluated across five datasets, 100s of tissues & cell types, human and mouse. A🧵below with my thoughts on how such tools will change how #Bioinformatics is done.

Exciting collaboration with Christina Jackson, MD, Drew Pardoll, Chetan Bettegowda, Vasan Yegnasubramani, and many others - now published in Science! Grateful for the contributions of our current and past group members: Runzhe Li, zhicheng ji, Wenpin Hou, and Wentao Zhan. #TeamScience