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Oh.

Automating experiments with AI is going to be really hard because automation is way less about high-dimensional Bayesian optimization than it is about figuring out why there are bubbles in your syringe pump line

Can’t imagine what international students at Harvard are going through It’s hard enough moving overseas in pursuit of higher education & training … couple that with being entirely unwanted by the government

“One of the biggest tragedies I've observed in my professional life.” David R. Liu, winner of the Breakthrough in Life Sciences and professor at the Broad Institute and Harvard University, describes the cost of government cuts to science research at universities. Walter Isaacson

Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to Yuichi FURUHATA, a true master bioengineer, on leading this excellent work! nature.com/articles/s4146…

retweeting bc I learned that posting on a friday afternoon is not a smart move. Please share widely and encourage others to reach out if they would like to be interviewed! Two more episodes of the podcast coming soon with Rachel Marsh and Steven Shuken ! shorturl.at/sAPUb

I was quoted in this very well done story by Mary Kekatos at ABC News highlighting some of the grants that were tragically and needlessly terminated including mine. abcnews.go.com/US/350-harvard…

At least 350 Harvard Medical School grants were among those terminated such as studying antibiotic resistance, identifying early precursors of breast cancer, breaking barriers to deliver effective drugs for Alzheimer's, and researching cures for ALS. ⬇️1/4 abcnews.go.com/US/350-harvard…

The White House Harvard University Thank you to Steven Shuken, David Sinclair, Michael Baym, Michael Desai and JOAN BRUGGE for taking the time to speak with me about their research and what the #HarvardUniversity grant terminations mean for them. 4/4

People have asked about how MAP-MS works so here's a tweetorial on Teeradon Phlairaharn's new preprint: biorxiv.org/content/10.110…. MAP-MS takes advantage of parallelization in a trapping MS, collecting Orbitrap MS1s with 2x the dynamic range by differentially amplifying parts of the ion beam.

If you're going to #ASMS2025, don't miss these presentations from members of the Gygi lab! You'll learn about TMT, chemoproteomics, GoDig for targeted proteomics, leveraging HMSBioPlex for drug discovery, new instrumentation, and much more! @edhuttlin Steven Shuken Amanda Smythers, PhD

.Secretary Kennedy - thank you so much for your broad support for gene editing and gene therapies as well as recognizing the importance of Baby KJ’s story and the potential that CRISPR base editing therapies hold for patients with severe genetic diseases. I’m thrilled you have publicly

Guy is speaking my love language

DOGE employee says "I personally was pretty surprised, actually, at how efficient the government was," fraud was minimal, and abuse was "relatively nonexistent" npr.org/2025/06/02/nx-…

How are big proteins washed out from CSF, if they can’t go through the glymphatic system? Here is how: our new finding on glymphatic bypass || nature.com/articles/s4159… Congrats Antoine and Ben Plog and thank you to our many collaborators!

The 2026 Chemistry Faculty Jobs List has 4 tenure-track positions: docs.google.com/spreadsheets/d… #facultychemjobs Faculty, if you know of tenure-track positions that we should be listing, or see an error, please e-mail us at [email protected]

This interview from the Soledad O'Brien Show captures some of the issues for women's health and our lab's cancer research affected by the termination of federal grants at Harvard and elsewhere youtube.com/watch?v=dtjZPt… Harvard Medical School AACR

it's interesting how many things in computation follow this pattern