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[x] PGY3 [x] first year of fellowship

A couple years ago, we showed that dietary fructose enhances intestinal tumor growth. Today, I’m excited to expand these results to the normal intestine and discuss the implications for obesity and cancer. nature nature.com/articles/s4158…

#OriginalResearch: Dysregulated phenylalanine catabolism abrogates healthy cardiac aging in a mouse model. A potential risk marker and therapeutic target for #CVD in the aging heart? ow.ly/oYpx50FUQ0M #AHAJournals Nadine

Friends don’t let friends write the Response to Reviewers’ Comments while hungry.

Excited to work with and learn from these stars and make exciting discoveries together and have fun along the way. In the words of Kobe Bryant, we don’t hang division banners 🐐

Fun to work on this editorial piece on an important question that has come up often as a fellow with the marvelous mentorship of Pradeep Natarajan and Michael Honigberg, MD, MPP. Many gaps in how we assess risk of ASCVD that don’t fall cleanly in primary vs secondary buckets and impact therapy

Our study led by Sumeet Khetarpal MGH Cardiology Fellows & D Rader Penn Genetics uses human & murine genetic studies to show that endothelial lipase, in addition to & in collab w/ lipoprotein lipase, is a regulator of TG-rich lipoprotein metabolism journals.plos.org/plosgenetics/a… PLOS Genetics

Does endothelial lipase (EL) contribute to triglyceride #metabolism? Khetarpal et al show that EL collaborates with lipoprotein lipase to break down triglyceride-rich lipoproteins, especially after a high-fat diet Sumeet Khetarpal Michael Levin Pradeep Natarajan doi.org/10.1371/journa…

Happy to share our new story published in Cell Metabolism regarding oral fructose tolerance test and blood glycerate measurements as a potential predictor of individual vulnerability to fructose-induced fatty liver disease. Awesome collaboration with Xia Yang Lab UCLA. Congrats all!

Circulation Research Compendium on #Cardiopulmonary Disease and #Exercise Molecular Mediators of the Cardiac Benefits of Exercise ahajrnls.org/4koVMxY Authored by Sumeet Khetarpal & colleagues Anthony Rosenzweig, MD Haobo LI, Ph.D.

Circulation Research Compendium on #Cardiopulmonary Disease and #Exercise Shen et al Research Letter "Exercise Mitigates #Diabetic #Cardiomyopathy by Suppressing #Ferroptosis via N-acetyltransferase 10" ahajrnls.org/44B3nnx 강민규 @sumeetkhetarpal