Stephen Mahler (@svmahler) 's Twitter Profile
Stephen Mahler

@svmahler

Behavioral neuroscientist. Ivan Pavlov fan. “Reward” circuits, addiction, neurodevelopment. #VP #Cannabis #DREADDs #Orexin #Opioids #Psychedelics?

ID: 2395053247

linkhttp://faculty.sites.uci.edu/mahlerlab/ calendar_today17-03-2014 20:22:37

5,5K Tweet

3,3K Followers

1,1K Following

katja heuer🐘k4tj4@mstdn.social🦋k4tj4.bsky.social (@katjaqheuer) 's Twitter Profile Photo

1 To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised! 🧵Thread on our new preprint with Roberto Toro [email protected] r3rt0.bsky.social , doi.org/10.1101/2025.0…

1
To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with <a href="/R3RT0/">Roberto Toro r3rt0@mstdn.social r3rt0.bsky.social</a> , doi.org/10.1101/2025.0…
Olivier George (@brainaddiction) 's Twitter Profile Photo

I’m really curious to hear what people think the best option is. My heart tells me $0 to radically reform the scientific publishing industry AND the Promotion & Tenure criteria in academia. My brain tells me perhaps we should find a middle ground and set it at $500-$2000 per

Olivier George (@brainaddiction) 's Twitter Profile Photo

hot off the press. thanks small miracle, if i'm reading this right the new senate bill would give NIH about the same budget as FY25 and all 27 institutes remains For neuro/addiction-related institutes: NIMH: $2.2B NIDA: $1,6B NIAAA: $0.6B NINDS: $2.6B SAMHSA: $2,8B Brain

hot off the press. thanks small miracle, if i'm reading this right the new senate bill would give <a href="/NIH/">NIH</a>  about the same budget as FY25 and all 27 institutes remains
For neuro/addiction-related institutes:
NIMH: $2.2B
NIDA: $1,6B
NIAAA: $0.6B
NINDS: $2.6B
SAMHSA: $2,8B
Brain
Olivier George (@brainaddiction) 's Twitter Profile Photo

Your brain after heavy cocaine use is just not the same. A new study using the long access cocaine IVSA model shows that microglia start trimming astrocytes during cocaine abstinence, and this is linked to increased craving. By blocking microglia-induced pruning using a peptide

Your brain after heavy cocaine use is just not the same. A new study using the long access cocaine IVSA model shows that microglia start trimming astrocytes during cocaine abstinence, and this is linked to increased craving. By blocking microglia-induced pruning using a peptide
Leah Mayo (@mayoonthebrain) 's Twitter Profile Photo

UCalgary is recruiting! We are recruiting for the Novartis Research Chair in Schizophrenia Research (MD required) See more info in the ad below, and feel free to reach out w/ questions about the institute, city, etc.,. Please share! universityaffairs.ca/search-job/?jo…

GenomicPress (@genomicpress) 's Twitter Profile Photo

🧵 Thread ⬇️ ✨ Exciting new Genomic Press Interview from our peer-reviewed journal Psychedelics by GenomicPress! Dr. Harriet de Wit just dropped a bombshell interview today revealing how 45 years of groundbreaking research has transformed our understanding of MDMA, LSD, and

🧵 Thread ⬇️
✨ Exciting new Genomic Press Interview from our peer-reviewed journal <a href="/PsychedelicsJnl/">Psychedelics</a> by <a href="/GenomicPress/">GenomicPress</a>! Dr. Harriet de Wit just dropped a bombshell interview today revealing how 45 years of groundbreaking research has transformed our understanding of MDMA, LSD, and
Neuropsychopharmacology (@npp_journal) 's Twitter Profile Photo

Did you catch this one? This recent review explored how the extended development of medial prefrontal cortex (mPFC) circuits makes them particularly sensitive to early life adversity nature.com/articles/s4138…

Bertoglio lab (FMC/UFSC) (@bertogliolab) 's Twitter Profile Photo

Pharmacological characterisation of psilocybin and 5-MeO-DMT discriminative cues in the rat and their translational value for identifying novel psychedelics doi.org/10.1177/026988…

Erica Marie Ramirez (@ramirezneurosci) 's Twitter Profile Photo

New Preprint!🚨 Silencing VP GABA neurons exaggerates defensive responses to threat cues ⚡️and activates the LHb, indicating a novel role beyond appetitive processing.🧠 Ty to all authors especially my now twitterless co-first, Maricela Martinez. Stephen Mahler biorxiv.org/content/10.110…

Conor Murray (@conormurray) 's Twitter Profile Photo

New cannabis paper: we focused on key age groups to track recent trends in cannabis use and reviewed health effects on brain and behavior across the lifespan — is the public becoming more health conscious about cannabis use? liebertpub.com/doi/10.1177/25…

Olivier George (@brainaddiction) 's Twitter Profile Photo

Review of 34 clinical trials (23 phase II) of psychedelics for the treatment of addiction. Promising results, but too preliminary. Most open-label, low N, lack of standard dose/measures. 26 with psilocybin, 4 with MDMA, 3 with ibogaine, 1 with DMT, with alcohol use disorder

Review of 34 clinical trials (23 phase II) of psychedelics for the treatment of addiction. Promising results, but too preliminary. Most open-label, low N, lack of standard dose/measures.
26 with psilocybin, 4 with MDMA, 3 with ibogaine, 1 with DMT, with alcohol use disorder
Dr. Millie Rincón-Cortés 🇵🇷 (@houseofmind) 's Twitter Profile Photo

Pleased to share our lab's latest research article🤓🐀 We followed up on our Oak 2024 study and found sex-specific effects of ELA on adolescent behavioral responses to natural rewards (sucrose in ♀️, play in ♂️) #SABV frontiersin.org/journals/behav…

Pleased to share our lab's latest research article🤓🐀 We followed up on our Oak 2024 study and found sex-specific effects of ELA on adolescent behavioral responses to natural rewards (sucrose in ♀️, play in ♂️) #SABV 

frontiersin.org/journals/behav…
Journal of Cell Biology (@jcellbiol) 's Twitter Profile Photo

.Lillian Fritz-Laylin et al propose a simple way to highlight both experimental #reproducibility & cell-to-cell variation, while avoiding pitfalls common in analysis of cell biology data hubs.la/Q03FmFjM0 📕 #Reproducibility & Best Practices in Cell Biology hubs.la/Q03FmFlB0

.<a href="/FritzLaylin/">Lillian Fritz-Laylin</a> et al propose a simple way to highlight both experimental #reproducibility &amp; cell-to-cell variation, while avoiding pitfalls common in analysis of cell biology data hubs.la/Q03FmFjM0

📕 #Reproducibility &amp; Best Practices in Cell Biology hubs.la/Q03FmFlB0
Anna Leshinskaya (@annaleshinskaya) 's Twitter Profile Photo

My department, UC Irvine Cognitive Sciences, is hiring at the Assistant Professor (tenure track) level. This is an incredible place to be--consider joining us! Applications due Nov 15th. recruit.ap.uci.edu/JPF09896

Jaweed Kaleem (@jaweedkaleem) 's Twitter Profile Photo

Trump wants UCLA to pay $1.2 billion to settle allegations it violated civil rights law. I took a look at the more than 7,300-word proposed UCLA settlement. Here's the detailed breakdown of Trump's plan to remake one of the nation's top public campuses: latimes.com/california/sto…

mbruchas (@mbruchas) 's Twitter Profile Photo

Pls check out the lab's newest preprint. Dopamine release and dynamics from LC-Noradrenergic Neurons. biorxiv.org/content/10.110…