Hi there! We're the Rubin Lab at Institute for Geographic Information Science and UC Berkeley. Follow us for news about cool microbiome editing research, happenings at the lab, and more! 😎🦠🧬

Join the team developing the new field of #microbiome editing! We are recruiting a jointly advised postdoc with Jennifer Doudna @doudna_lab to apply new CRISPR-Cas systems to editing clinically and environmentally relevant microbiomes. Learn more ⬇️ aprecruit.berkeley.edu/JPF03866

🚨New Preprint🚨How do diff 👶 gut microbiomes respond to the same human milk oligosaccharide (HMO) and why? Here, we used metagenomics and microbiome cultivation to examine inf-specific microbial interactions for 2'-fucosyllactose (2'FL) metabolism🧵: buff.ly/3ZFeUOT

The Rubin Lab recently celebrated the first anniversary of our lab with lunch! It’s been an awesome year of science and community-building (with many more to come)!! 🎉🤩

I’m really excited to share our new pre-print “Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi”, with co-first author Muntathar Al-Shimary @doudna_lab and the newly-minted Brady Cress lab! biorxiv.org/content/10.110… 🧵🧵 1/

Check out our latest paper that uses bacterial genetics to link tetrabromopyrrole production with coral morphogenesis. nature.com/articles/s4370…

🚨Thrilled to unveil Cress Lab's 1st pre-print! In work co-led with my former @doudna_lab-mates Ben Adler & Muntathar Al-Shimary, we establish a phage functional genomics platform to characterize the genomes of diverse lytic phages. 🧬biorxiv.org/content/10.110… 1/

Happy Halloween from the Rubin Lab and the Fellowship of the (Plasmid) Ring! 🦠🧝🧙‍♂️

so grateful for such a loving and wonderful lab!! excited for all the phenomenal science to come :)

It was a pleasure working with popo on this review of CRISPR-Cas associated transposons (CAST). Hopefully it gives a sense for the diversity of Tn7-like transposons and CRISPR systems that independently combined.go.shr.lc/444PwFh

🔬Join the Cress Lab UC Berkeley Institute for Geographic Information Science! We're hiring a Research Tech/Lab Manager to lead lab operations & support our research in phage engineering and precision microbiome editing.🧬🦠Apply here to be part of our innovative team! is.gd/4ol7Hj Retweets appreciated!

Congratulations to our undergraduate researchers Abby Wang and Danh Tran for receiving the 2024 UC Berkeley Rose Hills Summer Scholarships, which generously awards $5,000 to support undergraduate students in pursuing intensive research over the summer!

We’re thrilled to congratulate our stellar lab manager Leo Song on his grad school decisions and announce that Leo will be continuing with the Rubin Lab as a graduate student through the UC Berkeley Comparative Biochemistry department! 🎉🧬🐻🧑‍🔬

Excited about phage functional genomics, phage engineering, & microbiome editing? The Cress Lab UC Berkeley Institute for Geographic Information Science is hiring postdocs in these areas! Come chat w/ me Viruses of Microbes 2024 & don't miss my presentation w/ Ben Adler in the SynBio session Fri @ 11:20am. Retweets appreciated!

The Rubin Lab's first preprint is OUT on bioRxiv! ✨📄This lab-wide effort involved many amazing collaborations and fun conversations about the big wide world of CRISPR-associated transposons ⬇️ Thank you to our funders + everyone who contributed to making this project possible!

How does Hachiman work, and what can it teach us about immunity? Our structural and functional characterization of the Hachiman defense system is online: sciencedirect.com/science/articl… Thanks to co-lead Ben Adler, Emily Armbruster & coauthors at @doudna_lab. Institute for Geographic Information Science College of Chemistry HHMI

Recent work from the lab from Laura Chacon Laura Chacon Machado describing a family of Tn7-like transposons that evolved to target CRISPR repeats being presented at #cshlTE24 and now on bioRxiv biorxiv.org/content/10.110…

shouting out an organization near and dear to my heart: iGEM at Berkeley! we're crowdfunding this month to help fulfill our mission to break down barriers to undergrad synbio research-- learn more about how you can support us here ⬇️ crowdfund.berkeley.edu/project/43580/…

Cedric🧬➰🧬Feschotte popo Our preprint for this work is now on bioRxiv. This work also reveals a new type of guide RNA directed transposon, a type I-E CAST biorxiv.org/content/10.110…

🚨 The Alker Lab is starting at the University of Rhode Island in early 2025 and we will be hiring! 🚨 If you are interested in marine microbiology, bacterial genetics and/or symbiosis, please consider reaching out!