
Sylvia Villeneuve
@sylv_villeneuve
Associate Professor Department of Psychiatry, McGill University
Neuroimaging, MRI, PET, Alzheimer's disease
ID: 988845942660091904
http://villeneuvelab.com 24-04-2018 18:23:39
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🧠 Our lab’s latest deep learning-based tool ‘segcsvd’ to automatically segment white matter hyperintensities #WMH, now in HBM 🤩 A CNN-based tool trained on ~800 FLAIR MRI from multiple imaging sites covering a wide range of clinical populations 🔥 ➡️ onlinelibrary.wiley.com/doi/10.1002/hb…

👋New in Nature Mental Health Psychological profiles related to cognition and brain changes. Distinct pathways for dementia risk? @BBHI_Cat and SilverSantéStudy EU study with Marchant Lab Institut de Neurociències de la UB 👉nature.com/articles/s4422…


The Center for Precision Psychiatry - Québec is releasing a first batch of open access data on its transdiagnostic SPARK cohort of deeply phenotyped patients with psychiatric disorders. Researchers can access data here: cppquebec.ca/data @fondation_hgm Fondation Douglas | Douglas Foundation

🚨 New Study just out in The Lancet Global Health 🧠 Lucas Da Ros, Wyllians Borelli, Cristiano Schaffer Aguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other Latin American Countries 🧶1👇 thelancet.com/journals/langl…


In Nature Medicine, we show: 1. P-tau262 & P-tau356 as markers of pre-tangle tau pathology; 2. Identify a core region that defines soluble tau assemblies (STA); and 3. Validate CSF STA assay in autopsy & tau PET cohorts. Congrats to all coauthors! nature.com/articles/s4159…


New paper led by Aurélie Bussy now out in Neurobiology of ageing. We use non-negative matrix decomposition using morphological and qMRI measures (T1, T2*) to understand the relationship between GM and microstructure in the Alzheimer's spectrum. sciencedirect.com/science/articl…

A rare case of asymptomatic dominantly inherited Alzheimer's reveals confined tau pathology and unique proteomic features, highlighting potential resilience mechanisms decades beyond expected onset WashU Medicine Knight ADRC Jorge Llibre-Guerra nature.com/articles/s4159…


When someone with autosomal dominant AD beats the odds it is a time to celebrate. I'm captivated that tau pathology is contained in left occipital cortex, consistent with work from Yakeel T. Quiroz, PhD (she/her) . #Alzheimers Link to article below and also NPR story tinyurl.com/resistantADAD

ADPD! I'm excited to present the complete story of my WMH research: "Uncovering spatial pathophysiological patterns of white matter hyperintensities of neurodegenerative origins", including a cool new tractography analysis! Tue April 1st, Hall A, 12:45 #ADPD AD/PD - Advances in Science & Therapy



Hey #ADPD2025 , I'm happy to present our work on characterizing brain atrophy and cerebrovascular pathology in Frontotemporal Dementia subtypes! Tomorrow, April 5, 9:40am, Hall F2, session: Mechanisms and Clinical Trials in FTD, ALS, and Neurodegeneration 02 AD/PD - Advances in Science & Therapy


Tremblay et al. report similar, but less severe atrophy progression in individuals with Alzheimer's family history. It follows brain structural connections. Read: buff.ly/qfz9gCg Christina_Tremblay Shady Rahayel Dr. M. Natasha Rajah, PhD 🇨🇦 @ndrewvo Sylvia Villeneuve @FilipKMorys @alain_dagher



📢 Paper alert! Our new longitudinal PET & MRI study just came out in Neurology with an editorial — exploring how sex and parent’s sex impact Alzheimer’s pathology. Neurology Journal 🔗doi.org/10.1212/WNL.00… Huge thanks to collaborators, sponsors & my amazing mentor Sylvia Villeneuve

New longitudinal study from the lab exploring how sex and parent’s sex impact Alzheimer’s pathology led by Valentin Ourry Neurology Journal 🔗doi.org/10.1212/WNL.00……

🚨 New study by Müge Akıncı: we found that increasing physical activity over 4 years in midlife & new adherence to the World Health Organization (WHO) guidelines was linked to lower amyloid burden. Sustained sedentarism was linked to cortical thinning.🏃🏾♀️🧠 #Alzheimer #BrainHealth alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…


Our new Nature Communications paper: We used UK Biobank data (n≈193K) to build ML models predicting tinnitus presence (driven by hearing health) and severity (influenced by mood, neuroticism & sleep). A simple 6-item POST questionnaire forecasts 9-yr outcomes. shorturl.at/4AF4P
