Excited for this collaborative study by the twitter-less Stadtfeld group and Thomas Vierbuchen reporting a new role for neuroectpderm regulator OTX2 in the specification and anteriorization of Definitive endoderm biorxiv.org/content/10.110…

Excited to share our latest paper led by Rachel Glenn. We generated a genetically diverse mouse pluripotent stem cell panel from the Diversity Outbred stock and outline experimental approaches for "population-scale" in vitro directed differentiation. biorxiv.org/content/10.110…

Excited to share our latest manuscript. This was an exciting collab with the (twitter-less) Matthias Stadtfeld + Jason Mezey labs at Weill Cornell. We examined the impact of genetic variation on pathological loss of DNA methylation in naive PSCs. biorxiv.org/content/10.110…

Beyond excited to share my main postdoctoral work. We developed a robust mouse cortical organoid system, which recapitulates in vivo tempos and cellular diversity, and applied it to identify gene expression changes across subspecies during development. shorturl.at/9w0zT

Excited to share the latest work from my lab and Emily Wong led by Daniel Medina Cano Tarek Veronika Petrova. We developed a new protocol to generate mouse cortical organoids from pluripotent stem cells. Memorial Sloan Kettering Cancer Center Center for Stem Cell Biology at Sloan Kettering MSK ScienceEducation biorxiv.org/content/10.110…

See the published version of our pre-print (original twitter thread below). cell.com/developmental-…