🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

We are happy to share that Target 2035 will be featured in the upcoming International Chemical Biology Society 2023 with a scientific session chaired by Cheryl Arrowsmith. Among the speakers will be our very own Matthieu Schapira and Serah Kimani from Levon. More details: chemical-biology.org

“The hundreds of underperforming antibodies identified…were found to have been used in a large number of published articles” Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications elifesciences.org/reviewed-prepr…

Stefan Knapp and Susanne Muller talk about how different stakeholders can contribute to high-quality research using small molecule tools. nature.com/articles/s4158…

#AstraZeneca publishes on the challenges and impact on developing #highthroughput #thermalshift based #drugdiscovery High-throughput differential scanning fluorimetry (DSF) and cellular t... sciencedirect.com/science/articl…

Need a #chemicalprobe? @chemical_probes has reached 1000 chemical tools that have been reviewed by #drugdiscovery experts.

Wow!! Congratulations @BShoichet and others.

Nice work from Gray and Fischer Lab labs on combinatorial libraries for CRBN molecular glue discovery that yielded a WEE1 degrader. biorxiv.org/content/10.110…

This is a terrific and comprehensive review on molecular glues from the Arkin lab. Open access too. cell.com/cell-chemical-…

The short history of NSD2 degraders has been a little fuzzy with some odd mechanisms of action so far, but this one seems a little cleaner and more potent than its forebears. pubs.acs.org/doi/10.1021/ac…

#affinity_selection #hit_finding #drugdiscovery

🎙️ Get ready... Something BIG is coming from Target 2035! What if the future of drug discovery could be unlocked by listening in? Rachel Harding, Milka Kostić, PhD and Opher Gileadi got something brewing, and trust us- you won’t want to miss it! #Target2035, #OpenScience, #ComingSoon

🎙️ The Target 2035 podcast series is officially LIVE! In our pilot episode, meet our hosts - Milka Kostić, PhD, Rachel Harding and Opher Gileadi who share their personal motivations for joining the Target 2035 initiative. Tune in to the pilot episode now! podcasters.spotify.com/pod/show/targe… 🎧

📢RSC Medicinal Chemistry is delighted to announce our newest Associate Editor, Dr Susanne Müller-Knapp from Goethe-Universität! 📰Read our blog for more about Susanne: blogs.rsc.org/md/2024/10/21/… 👀Submit to her today: mc.manuscriptcentral.com/mcc Chemical Probes Portal Structural Genomics Consortium (SGC)

Just Launched! Episode 1 of the Target 2035 Podcast Series🎧 In the debut episode, Rachel Harding welcomes Cheryl Arrowsmith, a leading scientist in chemical biology and one of the initiators of Target 2035. podcasters.spotify.com/pod/show/targe… #Target2035 #OpenScience #DrugDiscovery

🚨 New publication alert! 🚨 Our latest update on the Chemical Probes Portal is live! 🎉 📜 Read the paper: doi.org/10.1093/nar/gk… 🔍 Learn about our expanded content + improved functionality in the 2024 Nucleic Acids Research Database Issue. #ChemicalProbes #BiomedicalResearch

A well anticipated overview highlighting the first CACHE challenge, which brought together 23 research teams from 10 countries to collectively predict 1,955 compounds targeting LRRK2-a protein linked to #ParkinsonsDisease. pubs.acs.org/doi/10.1021/ac…

A fully open framework for DEL-ML hit discovery. We replace explicit DEL compound structures with ML-ready chemical fingerprints, enabling the broad scientific community to advance DEL-ML models and refine discovery methods. All data available on AIRCHECK. chemrxiv.org/engage/chemrxi…

New episode for our Target 2035 Podcast Series 🎧 Milka Kostić, PhD talks with aled edwards to unpack his journey from a traditional research scientist to a passionate open science advocate. Listen here: bit.ly/3AZQkBm

#MAINFRAME is an #OpenScience Network, supported by Target2035 & ultra-large-scale experimental screening data, brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks tackling #DrugDiscovery challenges. aircheck.ai/mainframe

#MAINFRAME is launching! This international, #OpenScience Network brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks for tackling real-world challenges in #DrugDiscovery. Join us: aircheck.ai/mainframe