I’m really excited to share a new study from our group Cell . Led by phenomenal postdoc Junbing Zhang, who uncovered a nucleus-to-mitochondria ROS sensing pathway that plays an important role in mediating chemoresistance. sciencedirect.com/science/articl…

So excited to share our paper, now in press Cancer Discovery -- new, cheap, rapid blood assays show LINE-1 ORF1p is a biomarker useful for (early) detection of cancers (pan-carcinoma) & prognostics. ORF1p is highly specific and also appears useful in tissue. aacrjournals.org/cancerdiscover…

Thanks to an amazing team effort and great collaborators! Kathleen Helen Burns Johns Hopkins Medicine MGH Pathology Mass General Cancer Center Sam Klempner Dana-Farber Vikram Deshpande Omer Yilmaz David Ting SU2Cscience Wyss Institute Tomas Mustelin Vincent Center for Reproductive Biology MassGeneral News Ronny Drapkin