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Woohoo...AMAZING 🎺🎺🎺 Well done to The Royal Wolverhampton NHS Trust 🏥 who have recruited the 5⃣0⃣0⃣0⃣!!! #ibdpatient in CLARITY IBD 🎉🎉 Thank you for all your hard work #teamclarity. Devon goodies on the way to you. National Institute for Health and Care Research

I can't be the only one who is unexcited by the prospect of a purportedly more transmissible SARS-CoV-2 variant, possibly with mutations conferring partial antibody resistance, propagating in a UK population that is 'semi-immunized' for 12 weeks. Experiments in viral evolution...

How to spoil phenomenal results of the most important clinical trials of our generation 1. Extrapolate from 2-dose trials in >75,000 participants who all got 2 doses that 1-dose works fine 2. A UK gov't committee says the 2nd dose isn't needed until 12 weeks (only data is 3 wks)

Seroconversion rates following single dose of vaccine: data from CLARITY IBD.

U.K. IBD collaborative research delivers important data. Thanks to National Institute for Health and Care Research @NIHRSW Crohn's & Colitis UK 7000 patients and 92 U.K. hospitals. 👏👏👏 Please stick with the study, more data to follow.

People on immunosuppression therapies require timely access to the second dose of COVID-19 vaccines - News and Events - Crohn’s and Colitis Canada crohnsandcolitis.ca/News-Events/Ne…

He finally did it - and it is brilliant! Dr. Glaucomflecken #Gastroenterology #GI #MedTwitter

the french vaccination ad campaign is just *so good*

Self isolation rules still apply after 2 doses of vaccine. Two people out and about today have told me their children are at home isolating with pcr confirmed covid....

CLARITY IBD spin off paper. Blood tests at home and posted to the lab. Important adjunct to telemedicine. ⁦CLARITY IBD⁩ ⁦National Institute for Health and Care Research⁩ ⁦Crohn's & Colitis UK⁩ ⁦Research & Development at the Royal Devon⁩ ⁦Research at Exeter⁩ @exeteribd academic.oup.com/ecco-jcc/advan…

Research Square Covid-19 Preprints Latest antibody, AND brand new T cell data, from the Clarity IBD study available in this preprint. CLARITY IBD Tariq Ahmad Nick Kennedy NickPowellLab Charlie Lees

Latest CLARITY IBD out as a pre-print researchsquare.com/article/rs-755… After 2 doses of PZ or AZ vaccine: • IBD pts on infliximab have lower antibody responses • Antibodies decay over time BUT almost all have good T cell responses Suggests booster required & likely to be effective

Updated CLARITY IBD data

Took a look at the spike mutations in B.1.1.529 this evening, and colour coded them (details below)...there is...not much green.🧵

Wordle 228 2/6 ⬜⬜🟩🟨⬜ 🟩🟩🟩🟩🟩

Planning the next project with Exeter ibd research team. Watch this space

🚨 Alarming testimony from a doctor in the South of England🧵[1] “I’m a proud NHS physician. 30+ years qualified, 20+ years a consultant. I now work at a small district hospital, a microcosm of our dear, broken and dying NHS. The pre-covid cracks have now become huge gaping...

Hancock: I want £1,500 an hour Kwarteng: I want £1,250 an hour Dr Robert Laurenson Junior doctors want £19 an hour

Pleased to share our preprint exploring the transcriptional signatures associated with anti-TNF response in Crohn's disease patients from the PANTS cohort: medrxiv.org/content/10.110… 1/

A thread about medical taboo #101: Moving jobs as a consultant: After 5 happy years in London, I took the momentous decision to leave. It was almost as mochas a shock to me as it was to my colleagues, I thought I would stay forever, so why did I do it, and what did I learn? 1/11