🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

We have two new postdoc positions! We're looking for candidates with backgrounds in #physics, #optics, optical #engineering or systems neuroscience interested in designing, building, & applying #microscopy tools for #neuroscience. Pls retweet: vaziri.rockefeller.edu/open-positions/

So well deserved! Congratulations! Estef Azevedo

It was a fantastic day at Mount Sinai! I had the opportunity to learn so much from these incredible colleagues and thoroughly enjoyed every moment.

Congratulations Caleb!

So excited to finally share one of the most fun and exciting projects from my PhD! Here, Becca J. Carlson and I show that STING, a key player in the immune system, is a proton channel. Paper: lnkd.in/eQ6TXhvr MIT News Story: lnkd.in/eXExmjta

Over the moon about my postdoc work ⁦Science Magazine⁩ ! Ever wonder about how mammalian cells selectively degrade unwanted nuclear proteins without involving ubiquitination? Check out our paper on a non-canonical protein degradation mechanism! science.org/doi/10.1126/sc…

Delighted to share our collaborative efforts exploring the basis of leptin resistance in obesity. We address the long-standing enigma that obese humans and animals exhibit elevated leptin levels and show little response to exogenous leptin therapy. biorxiv.org/content/10.110…

Thrilled to share the first preprint from our lab on a expanded in vivo Perturb-seq platform, spearheaded by the very talented grad student Xinhe Zheng 💫 w close collaboration w Joshua Levin Sean Simmons Kwanho Kim (Broad) Xiangmin Xu (UC Irvine) -- check out the tweetorial!

Finally the “Browne lab” comes true! Congratulations Caleb!

What a wonderful journey this has been! Thanks to extraordinary colleagues!!!

We started the project by asking a simple question: how does the development of drug addiction interfere with our natural needs? This led us to collaborate across multiple fields to unravel the underlying mechanisms. I am truly grateful to work with these hardcore scientists!

Cori Bargmann (Cori Bargmann) has been named a 2024 recipient of the Gruber Neuroscience Prize! She is being recognized for her pioneering work elucidating the organization of circuits in behavior, and for developing new genetics tools. Congratulations! rockefeller.edu/news/35815-cor…

Excited to share my first paper from Inagaki Lab Max Planck Florida Institute for Neuroscience! How does the “timer” in our brain control movement? We discovered specialized computational roles of the frontal cortex and striatum that implement such an action timer⏱️ biorxiv.org/content/10.110…

A fundamental study delineates the intracellular signaling of teneurin!

‼️my PhD work is officially out Nature Communications 🚀 We dive into “Genetically- and spatially-defined basolateral amygdala neurons for multimodal stimulus “ and can’t wait for you to explore our findings:doi.org/10.1038/s41467… 📖🔍 #neuroscience with R.Klein MPI for Biological Intelligence

A new accumbal cell type that connects to leptin signaling in the hypothalamus. Very thorough and novel work!

My PhD paper is out! We imaged gut neuron activity in living, eating flies (first time in history!), and found a Gut-Brain-Gut neural circuit loop that allows fruit flies to adjust their ingestion bouts based on the sucrose concentration of the food! (1/n biorxiv.org/content/10.110…

Thrilled to share our paper online nature (on my birthday)! We've identified a new population of LepR neurons (BNC2) in the hypothalamus ARC that acutely suppresses appetite by directly inhibiting AGRP neurons, decoding the missing LepR GABAergic neurons. nature.com/articles/s4158…

A prelude: 1. Humans with obesity have high endogenous leptin levels. 2. Exogenous leptin is insufficient to reduce weight in these individuals. 3. Leptin resistance is thought to involve a putative block in the brain. What are the biological substrates of this putative block?