🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

❗️Publication❗️ Head-to-head comparison between a highly accurate plasma biomarker and FDA-approved and clinically used CSF biomarkers 🩸#ptau217 is clinically comparable or superior to CSF biomarkers to detect #Alzheimer's pathologies Nature Medicine nature.com/articles/s4159…

‼️ Postdoc ad // Please RT/circulate ‼️ Are you interested in * Big euroimaging and multi-omic data? * Neurodegenerativ disease? The BioFINDER is looking for a talented postdoc to sink their teeth into some rare and exciting data! Apply here: lu.varbi.com/en/what:job/jo…

Wonderful summary by Hanny Le from our team documenting EEG spectral signature similarities and differences amongst the available psychedelics. Helpful guidance for research and mechanistically informed development pubmed.ncbi.nlm.nih.gov/38570038/

Todays lunch seminar offered many captivating talks! We learned by Toomas Erik Anijärv 🇪🇪 the impact of asymmetrical #tau aggregation in #AD, by Srisaiyini Kidnapillai about the current advances in glia to #interneurons #reprogramming, and by Filip Fredlund how #MHCII impact #PD pathology.

🚨New publication out in Nature Communications led by Linda Karlsson! We introduce CSF reference proteins: a way to account for the non-disease related signal in CSF protein levels that varies between individuals and affects biomarker performance. doi.org/10.1038/s41467… Detailed 🧵👇

🚨Paper alert Led by PhD student Sophie Mastenbroek “Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology” now published in Nature Communications ! nature.com/articles/s4146… We found a novel brainstem-first Lewy body subtype 👇

Super proud to be #Estonian as we are again one step closer to medicine 4.0. Besides different health risks, I also now know I’m 2.51% neanderthal and my ancestry reaches even Asia. nature.com/articles/d4158…

I am hiring a research technician to help process and analyze multimodal neuroimaging data. Please RT!! * Great opportunity to gain research experience pre-PhD * Access to exciting data * Opportunities for independent projects Apply here: lu.varbi.com/en/what:job/jo…

My first paper, entitled “CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer’s disease”, has been published in Alzheimer’s & Dementia Alzheimer's & Dementia Journals! Thread 👇🏽

🚨Publication in JAMA 🚨 Blood biomarkers to detect Alzheimer’s disease in primary and secondary care, published today in JAMA led by Sebastian Palmqvist: jamanetwork.com/journals/jama/…

The figure we all have to learn by heart: The updated Lancet Commission on potentially modifiable risk factors for dementia. #AAIC24

Big thanks to the BioFINDER team for two great days! During our workshop we sharpened our visions for the future, optimized our database structure and learnt from the clinicians how different clinical assessments are done.

Interested in combining neuroimaging and multiomics in AD? Check out our new review on this topic, just published in Cell Reports Medicine. We focus on integration with amyloid- and tau-PET and all the challenges that come with it. w/ Niklas Mattsson-Carlgren cell.com/cell-reports-m…

Check out Alicia Campbell ‘s first paper, part of her PhD on the neurophysiological mechanisms of sustained attention and aging!

Cortical maps manifest hemispheric asymmetry in various forms and scales. Our attempt to unveil them through 🧠 eigenmodes: doi.org/10.1101/2024.1… Work led by Alicia Milloz✨

📢The CHMP recommends authorising a new treatment for early #AlzheimersDisease in the EU. Leqembi is intended for treatment of mild dementia and cognitive impairment in a restricted patient population with a specific genetic make-up. 👉 ema.europa.eu/en/news/leqemb…

🧠New preprint alert! Tau, the pathological protein in AD, spreads through the brain in a very particular pattern. But what drives this pattern? We found that WHERE tau pathology appears, and HOW MUCH accumulates there, are governed by different mechanisms. Check out our

The preprint of my first PhD project is live! 🧠 Find the link to the manuscript and read about the key findings below. 👇 #alzheimersdisease #neuroimaging #tau #amyloid #mri #pet #biofinder

Individuals with more severe clinical Alzheimer disease symptoms than their biological stage often have additional pathologies. ja.ma/3H0b6TU

How does the brain reorganize in the context of age and AD? Are functional changes in age and AD similar? Are these changes dynamic across the age/AD spectrum? We unpack these questions in a sample of N=973 with AD biomarkers Preprint: tinyurl.com/ymv8s7h8 1/ ⬇️🧵