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Happy to see the fantastic work by Maxim Zaslavsky, Scott_Boyd_Lab_Stanford and coworkers finally out in Science Magazine. Great demonstration of the potential of AIRR-Seq based diagnostics | science.org/doi/10.1126/sc…

Excited to announce a call for submissions for a special collection on T cell responses to influenza that I'm guest editing! If you're doing research in this area, I encourage you to submit your work. Feel free to reach out for information and see below. #BMCimmunology #Tcells

My co-first author paper was out. Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma nature.com/articles/s4146…

Feature selection methods affect the performance of scRNA-seq data integration and querying❤️ nature.com/articles/s4159…

scRepertoire now has a function to remove TCR/BCR VDJ genes from the variable features used for dimensional reduction. Friends don't let friends bias their clusters with indirect measures of clonal expansion. borch.dev/uploads/screpe…

Attention T cell biologists! New required reading from the one and only Golnaz Vahedi on how the epigenome directs T cell fate and function. nature.com/articles/s4159…

Happy #MatchDay to our new WashU Medicine Pathology & Immunology residents! We’re all excited and eager to work with you!

Incredible, neither data nor code nor weights are being made publicly available. nature publishes advertisements as Articles now I guess.

Wait tell they see your new paper!! The All-In Podcast thanks for the shout out!!

1/15 Want to decode pathway activity in single cells? Understand ssGSEA, GSVA, AUCell, and UCell—tools that score gene sets per cell. Here's how they work 🧵

Nitin Karandikar, MD, PhD, has been named the enterprise chief strategy officer for University of Iowa Health Care, expanding his executive leadership responsibilities while he continues as professor and chair of the Department of Pathology. uihealthcare.org/.../karandikar…...

Delighted to share our recently published work in Nature Immunology. We show here that normalized microbial exposures in mice enhance memory T cell surveillance of the brain and modify seizure outcomes. nature.com/articles/s4159…

Can a cancer exploit its environment and still resist treatment? Yes, through co-existing malignant subclones! Let me walk you through our latest study on how divergent evolution drives aggressiveness, and drug resistance of T cell cancer. 1/🧵 doi.org/10.1158/2159-8…

dandelionR: Single-cell immune repertoire trajectory analysis in R is out! sciencedirect.com/science/articl… Checkout our package at github.com/tuonglab/dande… and on Bioconductor 3.21 onwards! Thanks to everyone involved! Nick Borcherding

scRepertoire now supports exporting clones directly into the immunarch workflow ImmunoMind.. Immune cells crosstalk, why not R packages? Vignette: borch.dev/uploads/screpe…

Researching at the intersection of HLA and viral infections - check out the special issue from Viruses. mdpi.com/journal/viruse…

TCR2HLA: calibrated inference of HLA genotypes from TCR repertoires enables identification of immunologically relevant metaclonotypes biorxiv.org/content/10.110… #biorxiv_immuno