It blows me away that UC San Francisco is out here fighting for open access for all UC papers in Elsevier but wants to charge me extra to make my thesis open access.

.James Fraser (A$AP J) #fljcnlt Comparing models with variable number of parameters using information criterion: AICc and BIC smr.sagepub.com/content/33/2/2…

.James Fraser (A$AP J) #fljcnlt Positioning of the catalytic base in ketosteroid isomerase ncbi.nlm.nih.gov/pubmed/24597914

.James Fraser (A$AP J) #fljcnlt Dynamics and catalysis of cyclophilin proteins ncbi.nlm.nih.gov/pubmed/26335054

.James Fraser (A$AP J) #fljcnlt Fundamental challenges in determining contributions to enzymatic rate enhancements vs solution ncbi.nlm.nih.gov/pubmed/23488725

.James Fraser (A$AP J) #fljcnlt Improved prediction of stable sequences using negative multistate design ncbi.nlm.nih.gov/pubmed/26412333

.James Fraser (A$AP J) #fljcnlt Maximum entropy and maximum caliber review journals.aps.org/rmp/abstract/1…

.James Fraser (A$AP J) #fljcnlt MUMO: minimal underfitting and overfitting: ubiquitin ensemble #PDB:2nr2 ncbi.nlm.nih.gov/pubmed/17225069

.James Fraser (A$AP J) #fljcnlt Ordered solvent positions for each amino acid in different conformations ncbi.nlm.nih.gov/pubmed/26527137

.James Fraser (A$AP J) #fljcnlt R factor gap in macromolecular crystallography - inadequacies of current models ncbi.nlm.nih.gov/pubmed/?term=2…

.James Fraser (A$AP J) #fljcnlt The other side of macromolecular crystallography - the solvent. ncbi.nlm.nih.gov/pubmed/25945568

.James Fraser (A$AP J) Using kinetic crystallography to study the dynamics of insect carboxylesterase. sciencedirect.com.ucsf.idm.oclc.org/science/articl… #fljcnlt

.James Fraser (A$AP J) #fljcnlt Studying the conformational states of a highly flexible loop in Indoleamine dioxygenase ncbi.nlm.nih.gov/pubmed/?term=2…

.James Fraser (A$AP J) #fljcnlt Changes in active site water upon mutation in Aristolochene synthase ncbi.nlm.nih.gov/pubmed/?term=2…

World's biggest laser gets an upgrade: ✔1000x more powerful ✔10000x brighter ✔8000x faster 1.usa.gov/28LF8s4 amp.twimg.com/v/7df75f01-235…

.James Fraser (A$AP J) #fljcnlt Biophysical study of water dynamics extending from protein-water interface. ncbi.nlm.nih.gov/pubmed/27339138

.James Fraser (A$AP J) #fljcnlt 2nd-shell mutations enhancing phosphotriesterase function of promiscuous AiiA lactonase ncbi.nlm.nih.gov/pubmed/?term=2…

.James Fraser (A$AP J) Modeling an unbound + ligand-bound ensemble improves crystal structures: biorxiv.org/content/early/… #fljcnlt #preprint #biorxiv

Flexibility and design: conformational heterogeneity along the evolutionary trajectory of a ... biorxiv.org/cgi/content/sh… #bioRxiv

New #preprint in #bioRxiv. Directional conformational cycling of enzymes out of equilibrium #fljcnlt x.com/MichaelKGilson…