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Paradigm shift: #aHUS is driven by activation of the CLASSICAL pathway thru autoreactive IgM! The APC amplifies the stimulus but is not the dz driver. Blood Journal International Complement Society Complement Kidney TMA UK ASH Kidney International #complement #aHUS doi.org/10.1101/2024.0…

New assay to diagnose aHUS -> Bioluminescent mHam. Science Translational Medicine Science Immunology

The CBC is the most common blood test. Don’t let abnormal parameters get you flustered… Learn the “why” & you can master interpretation of any test! Being on The Curbsiders was my #hemedream come true!! Check out our LIVE! episode: Macrocytosis made “retic-ulously” simple. 😉

#SickleCell is the most common monogenetic disease in the world. No better way to celebrate World Sickle Cell Day than to light up the iconic Johns Hopkins Medicine Dome red! Shout out to our Johns Hopkins Hematology #HemeDreamTeam who are tireless advocates for our #sicklecell patients!

Out in Blood (first edition). Thx to reviewers who encouraged us to prove classical pathway stimulus on multiple cell surfaces including endothelial cells (HMEC1) shown below. Commercialization coming!

Most powerful diagnostic and monitoring assay for aHUS/CM-TMA now available. #ASH24 Can also monitor any complement inhibitors used for PNH, M. Gravis, CAD etc.