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Prof Darrell J. Irvine was elected to the National Academy of Medicine for 2023 “for the development of novel methods for delivery of immunotherapies and vaccines for cancer and infectious diseases.” news.mit.edu/2023/researche… National Academy of Medicine

Check out Luciano’s exciting work on cytokine CD45 targeting!! 👇🏼

Podcast🎙️: Frontier of Immunological Engineering w/ Darrell Irvine 🚀Explore Darrell Irvine's journey from physics to #Immunology and future predictions for 2050. Discover vaccine & T-cell innovations! Shoutout: Alloy Therapeutics, Inc., Ankyra Therapeutics & more buff.ly/3HoLVHH

Thank you Dr. Topol for sharing our study! Prof. Akiko Iwasaki Charles Dela Cruz Mario Peña-Hernández 🇲🇽

One way to enhance #PandemicPreparedness is to discover/repurpose drugs against novel pathogens. In our new manuscript, we repurpose an antibiotic that is currently broadly available and potentiates the innate immune system against respiratory viral infections. 👇

Congrats to Tianyang Mao and all authors on this study! Intransal neomycin protects against viral transmission! And very neat proof-of-concept data that intranasal neomycin induces ISGs in people.

#InterferonPower! Prof. Akiko Iwasaki Mao &co show PNASNews that intranasal administration of an #antibiotic induces #IFN-stimulated genes that protect mice from lethal #influenzaAvirus & #SARSCoV2, hamsters from spreading the virus, & induces ISGs in humans doi.org/10.1073/pnas.2…

Immunology is for everyone! Excited to share "Exploring new perspectives in immunology" with Ruslan Medzhitov in Cell. sciencedirect.com/science/articl…

A new study led by Mario Peña-Hernández 🇲🇽 in collaboration with the Craig Wilen examines two bat coronaviruses that are the closest relatives of SARS-CoV-2 for their ability to infect, evade immunity and transmit between rodents. Some key takeaway points 🧵 (1/) nature.com/articles/s4156…

Thrilled to share the first publication of my Ph.D. thesis today in @naturemicrobiol with @wilenlab and @virusesimmunity. Here we synthesized, recovered, and studied two of the closest known relatives of SARS-CoV-2 from bats that were recently discovered in Laos to assess their

Our latest one is out nature ! We found an aberrant immune epithelial progenitor niche drives post viral lung inflammation and fibrosis #LongCovid. We also pointed out potential therapeutics. nature.com/articles/s4158… Shout-out to Harish Narasimhan and Wei Qian Peter Chen Chongzhi Zang

Great news! Self-administration is now possible for nasal spray influenza vaccine #FluMist 👃🏼💦 This is a big step in the right direction

Incredible work led by Miyu Moriyama on unadjuvanted nasal boosters for influenza viruses! Important implications for eliciting immunological protection against avian flu via mucosal vaccination. Congrats to everyone involved in the study!

This incredible discovery of natural antibody recognition of viral gycans by Yexin Yang is the result of her meticulousness, creativity, and perseverance. So satisfying and inspiring to watch this story unfold and take so many unexpected turns during my PhD. Congratulations to all!!

The measles vaccine is given as a shot but it is surprisingly good at inducing protective immunity in the respiratory tract (mucosal IgA). Our new study Yale School of Medicine and Johns Hopkins Bloomberg School of Public Health provides some clues about why...a thread (1/8) academic.oup.com/jid/advance-ar…

Check out this exciting new pub by Rumya on rational design of immunogenicity-attenuated Cas9 and Cas12a. A important step forward in gene therapy - congratulations!!

Published today📣 Our nasal booster in the "Prime & Spike" vaccine works without adjuvants (which are needed to induce adaptive immunity but also cause inflammation). Dong-il Kwon 🇰🇷 Tianyang Mao Benjamin Israelow et al. asked how this is possible. (1/) nature.com/articles/s4159…