So excited to share our work out in Nature Immunology !!! We analyzed antigen-specific CD8 T cells differentiating down effector/memory vs exhaustion (Exh) lineages using scRNAseq/scATACseq. Major findings 👇 E. John Wherry Penn Medicine nature.com/articles/s4159…

Everyone at #SITC22 should come to the SITC Early Career Scientist Committee networking event tonight at the Omni at 9 PM! Fun party, great colleagues, free food and drinks!

Our lab is hiring! We are looking for a Research Assistant interested in studying how obesity reprograms the immune system and leads to inflammatory diseases. Please apply to join the fantastic @VUMC_VCI research community! ⬇️ loom.ly/KzBI4mw or DM

Ager Lab postdoc position currently open! More to come. Please share! Also feel free to DM if interested. jobs.mayoclinic.org/job/scottsdale…

Check out our latest article!!

Great work by Andrew Patterson to show IEI & IEM share more than previously known--a CRISPR resource for new immunometabolic genes Functional Overlap of Inborn Errors of Immunity and Metabolism Genes Define T Cell Immunometabolic Vulnerabilities biorxiv.org/content/10.110…

Novel Murine Glioblastoma Models That Reflect the Immunotherapy Resistance Profile of Human Disease academic.oup.com/neuro-oncology…

Hot off the presses! Our mxIHC analysis pipeline. Great teamwork including @IhrieLab Jonathan Irish Christine Lovly, MD, PhD, FASCO LisaCoussens@CoussensLab Alignment, segmentation and neighborhood analysis in cyclic immunohistochemistry data using CASSATT onlinelibrary.wiley.com/doi/10.1002/cy…

Excited to share my work in the @IhrieLab detailing a new potential regulatory mechanism of the quiescence entry that preserves neural stem cells in the embryo for the adult brain. Vanderbilt School of Medicine Basic Sciences

Interested in how metabolism of immune cells within the TME can drive tumor progression? Check out our new review in ⁦Cancer Cell⁩! ⁦⁦Jeff Rathmell⁩ cell.com/cancer-cell/fu…

🎯 preprint highly collaborative publication @IhrieLab Irish Lab @ VU Mary Chalkley, Ph.D. Laura Geben "Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence" biorxiv.org/content/10.110… Vanderbilt School of Medicine Basic Sciences

🔬 Nice publication from the @IhrieLab Irish Lab @ VU lab "Learning cell identity in immunology, neuroscience, and cancer." link.springer.com/article/10.100… Vanderbilt School of Medicine Basic Sciences

Register for the free SITC-National Cancer Institute Comp IO 2023 webinar series. Led by experts in the field, this 8 webinar series will help individual research labs embrace the computational challenges of analyzing and integrating diverse data across the spectrum of IO. sitcancer.org/CompIO

Spotlight on AAI Journals (Sat. @ 10:15 Rm 202B) panelists: Nitya Jain, PhD Todd Bartkowiak @taylor_tct, ObarLab Zhichao Fan & Vanessa Espinosa | highlight papers recently published in The Journal of Immunology & ImmunoHorizons #societypublisher #AAI2023

.Dionysios (Dennis) Watson and Defne Bayik, researchers and co-first authors of a groundbreaking, preclinical study, identified how #glioblastoma cells obtain fuel to become aggressive and new ideas on how to target the deadly #BrainCancer. Learn more: loom.ly/_Ii9ehc

What a great opportunity to share our work on IEI and the effect of IL-6 on immunometabolism in patients with STAT1-GOF mutations! The American Association of Immunologists (AAI)

Lateral ventricle-contacting glioblastomas have a distinct immunosuppressive microenvironment: buff.ly/3qPO7CO Jonathan Irish @IhrieLab @lolachambless Todd Bartkowiak Vanderbilt Health #Immunology #Oncology

🎉Exciting Update of scGPT 🎉: After receiving significant attention from the community since our April release, we're thrilled to announce the first major update for scGPT - a foundation model for single-cell multi-omic data. This update integrates community feedback and

Thrilled to be defending my dissertation next week to be receiving my PhD from Vanderbilt School of Medicine! It's been a great 5 years in the @IhrieLab and Vanderbilt Pharmacology and I'm excited to share some of my work with the community. 🧪🧠🐭 Zoom link available if you're interested. VandyBiomed

We've also recently published on the clinical and immunological impacts of a novel CTLA4 mutation in a large kindred. Led by Jimmy Maiarana, our multi-talented R38 resident doi.org/10.1111/pai.13…