Tej Pratap Singh (@tpsinglab) 's Twitter Profile
Tej Pratap Singh

@tpsinglab

Cellular immunologist exploring the complex interactions of immune cells and microbiota in skin.

ID: 1453562040925237249

calendar_today28-10-2021 03:19:53

109 Tweet

58 Followers

181 Following

John Streicher (@johnstreicher1) 's Twitter Profile Photo

Admissions tip - we’re not primarily selecting candidates based on “merit.” We’re selecting based on “how likely are they to successfully complete our program.” That is our primary concern, student success. Apply accordingly.

Tej Pratap Singh (@tpsinglab) 's Twitter Profile Photo

Old but still gold in my heart: UVR as a treatment for psoriasis and crucial role for Foxp3 Treg cells @PennSbdrc Penn Vet 8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ reg… pubmed.ncbi.nlm.nih.gov/20488788/

Tej Pratap Singh (@tpsinglab) 's Twitter Profile Photo

A journey from work to home is about more than just getting there – the psychological benefits of commuting that remote work doesn't provide theconversation.com/a-journey-from… via The Conversation U.S.

Waggoner Lab (@labwaggoner) 's Twitter Profile Photo

Colonic RORγ+ Treg cells seed non-mucosal tissues in response to injury wherein they can rein in IL-17A-driven inflammation, regulate stem cell activities, and promote tissue regeneration Immunity Bola Hanna MathisLab cell.com/immunity/fullt…

Camila Farias Amorim, Ph.D (@amorim_cfa) 's Twitter Profile Photo

Using Foxp3+ Treg cell counts, we categorized patients in a skin #RNAseq dataset. In Leishmania+S.aureus co-infection cases, low Foxp3+ Treg levels connect to harmful IFN-g #inflammation and slower healing, unveiling its dual role in infections. #NGS #datawrangling #translational

Journal of Experimental Medicine (@jexpmed) 's Twitter Profile Photo

Insights from Mihalis Lionakis: Mibrobial dysbiosis worsens cutaneous leishmaniasis. Tej Pratap Singh, Scott Lab et al (bit.ly/3MgOlen) show that Rorγt+ regulatory T cells suppress pathogenic IFN-γ responses to control Staphylococcus aureus growth bit.ly/48Y7iMy

Insights from <a href="/LionakisLab/">Mihalis Lionakis</a>: Mibrobial dysbiosis worsens cutaneous leishmaniasis.  <a href="/tpsinglab/">Tej Pratap Singh</a>, <a href="/pscottlab/">Scott Lab</a> et al (bit.ly/3MgOlen) show that Rorγt+ regulatory T cells suppress pathogenic IFN-γ responses to control Staphylococcus aureus growth bit.ly/48Y7iMy
Tej Pratap Singh (@tpsinglab) 's Twitter Profile Photo

We highlight how the human microbiome can shape disease outcomes in cutaneous leishmaniasis and suggest pathways toward host-directed therapies to mitigate the inflammatory consequences. Nice work Camila Farias Amorim, Ph.D Microbiome and You @RNAseq Immunology science.org/doi/10.1126/sc…

Vijay Rathinam (@rathinamva) 's Twitter Profile Photo

How do systemic PAMPs become accessible to cytosolic PRRs in vivo? Thrilled to have our work out Nature Cell Biology showing Host EVs capture and escort systemic LPS to cytosol activating Casp11 & pyroptosis. Congrats to Puja Puja Kumari, who led the work. 1/3 nature.com/articles/s4155…

How do systemic PAMPs become accessible to cytosolic PRRs in vivo? Thrilled to have our work out <a href="/NatureCellBio/">Nature Cell Biology</a> showing Host EVs capture and escort systemic LPS to cytosol activating Casp11 &amp; pyroptosis. Congrats to Puja <a href="/dolly_puja/">Puja Kumari</a>, who led the work. 1/3 nature.com/articles/s4155…
Arjun Raj (@arjunrajlab) 's Twitter Profile Photo

Being a mid-career professor is different in a lot of ways from being junior faculty. I worry we are not providing them with the support they need to grow in their jobs, potentially squandering the talent we invested decades in nurturing. (Not just funding.)

Ivan Zanoni (@lo_zanzi) 's Twitter Profile Photo

Fantastic ⁦nature⁩ by Nir Hacohen &co! They created gene transcription maps at the single cell level for 17 different cell types in the lymph node in response to each of the 86 cytokines & develop a tool to infer from RNAseq data cytokine activity! nature.com/articles/s4158…

Tej Pratap Singh (@tpsinglab) 's Twitter Profile Photo

Intestinal inflammation is driven by unrestrained activation of IFNγ-producing CD4+ T cells and depletion of peripherally induced regulatory T cells through Fcγ receptor signaling.

Journal of Experimental Medicine (@jexpmed) 's Twitter Profile Photo

.Tej Pratap Singh et al. reveal that Treg levels function as a rheostat, controlling bacteria in the skin & influencing whether bacteria induce IL-17 or IFN-γ-mediated immunopathology hubs.la/Q02kSFC90 In our Barrier Immunity collection: hubs.la/Q02kSy4j0 #KSBarrierReg24

.<a href="/tpsinglab/">Tej Pratap Singh</a> et al. reveal that Treg levels function as a rheostat, controlling bacteria in the skin &amp; influencing whether bacteria induce IL-17 or IFN-γ-mediated immunopathology hubs.la/Q02kSFC90

In our Barrier Immunity collection: hubs.la/Q02kSy4j0
#KSBarrierReg24
Journal of Experimental Medicine (@jexpmed) 's Twitter Profile Photo

Barriers sites are characterized by complex immunological crosstalk between pathogens, commensals, and the immune system. Explore this collection highlighting recent JEM papers dissecting barrier immunity at the epithelial and neurovascular barriers. ➡️ hubs.la/Q02kSy9_0

Barriers sites are characterized by complex immunological crosstalk between pathogens, commensals, and the immune system. Explore this collection highlighting recent JEM papers dissecting barrier immunity at the epithelial and neurovascular barriers. ➡️ hubs.la/Q02kSy9_0