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Academics agreeing to exciting new papers & projects…

In relatives screened for familial #DCM, genetic testing and findings on baseline ECG and #EchoFirst can accurately identify relatives at low risk of developing disease during a median follow-up of 5 years jacc.org/doi/full/10.10… JACC Journals christoffer vissing #JACCHF #HeartFailure

A new efficient strategy for screening family members of patients with Familial Dilated Cardiomyopathy. How do you think it will affect your practice? shorturl.at/ERS38 christoffer vissing #Screening #FamilialDilatedCardiomypathy #FDC

New in #JACCHF: A new efficient strategy for screening family members of patients with familial dilated cardiomyopathy. How do you think it will affect your practice? bit.ly/3UGbOHn christoffer vissing #Screening #FamilialDilatedCardiomypathy #FDC

📣PhD defence📣 Dr. christoffer vissing is defending his PhD thesis "Precision medicine in inherited cardiomyopathies - Predictors, novel treatments, and new disease mechanisms" tomorrow Dec 9 at Rigshospitalet (Aud 2) 🎉🎉 Principal supervisor Prof. Henning Bundgaard 🫀🩺 See you there!

Glad to see #CVgenetics so prominently highlighted in #JACCHF JACC Journals by BiykemBozkurt #THT2023 christoffer vissing Cardiovascular Research Foundation mathew.maurer Ahmad Masri iacopo olivotto A/Prof Jodie Ingles @DrNasrien CVGenomics Elizabeth McNally Alin Gragossian, DO, MPH Jane Wilcox, MD, MSc Nosheen Reza, MD, MS W. H. Wilson Tang, MD

Fantastic work from Kathryn McGurk James Ware and the CVGenomics team. Hidden amongst the many gems in this work are updated prevalence estimates for #HCM (1:543) and #DCM (1:220). Even more striking- the enormous 🚺🚹 differences in penetrance 🤔 Cardiomyopathy UK

Excited to report our collaborative efforts to better understand mechanisms behind beneficial effects of ARB in early-stage HCM! ahajournals.org/doi/abs/10.116… Thanks to christoffer vissing @sday_hcm Henning Bundgaard Anjali Owens Carolyn Ho Brigham and Women’s Cardiovascular Life Science Brigham and Women’s Research and many others

Great update from the LIVE-HCM study! Kudos to all the investigators and study participants. Let's put an end to any formal or perceived need for exercise restrictions in HCM. Let's promote a healthier future!

#ICYMI: LV systolic dysfunction in childhood-diagnosed HCM Sarah Abou Alaiwi christoffer vissing Carolyn Ho Brigham and Women's Hospital Brigham and Women’s Research #AHAJournals

Our study on the effect of valsartan on disease progression in subclinical HCM is out now in JAMA Cardiology doi.org/10.1001/jamaca…. Overall, progression of HCM was slow and no effect of valsartan was identified (although n=34). Thanks to all patients and collaborators!

Excited to share our collaboration with Dr. Gavin Oudit where we noted that 44% of heart transplant patients have damaging genetic variants in cardiomyopathy genes. Important that we consider genetic testing in patients with non-ischemic cardiomyopathy! #HeartFailure #genetic

🔬 Exciting news! Our latest study, published in JACC Journals, investigates an understudied aspect of TTNtv – its impact on skeletal muscle. We report findings indicating an effect of TTNtv beyond the heart. Dive into the full study here: authors.elsevier.com/a/1i85H7tD%7EZ… 🧬

Let me tell you a story about 2 patients we identified via a research study, both with a rare variant in the cardiac troponin T gene, TNNT2; NM_001001430.3: c.571-1G>A. Both had cardiac phenotypes and both had Oceanian ancestry /1

Now out Circ: Heart Failure , led by 🌟Cristian Topriceanu, we test CV biomarkers Olink Proteomics in the VANISH Trial to differentiate subclinical vs early HCM. Nt-proBNP best tracked disease progression while multi-marker panels added clinical and biological insight into HCM trajectory