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Check out our latest work...

Excited to share that my very first paper as a lead author is now published Angewandte Chemie . Many thanks to Muhammad Jbara and all labmates.

Thanks Angewandte Chemie for selecting our paper as a Very Important Paper! #AngewandteVIP The final version of this work has appeared today #OpenAccess onlinelibrary.wiley.com/doi/10.1002/an…

Deciphering the Role of the Ser-Phosphorylation Pattern on the DNA-Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis (Muhammad Jbara and co-workers) Muhammad Jbara, Tel Aviv University, Ariel Afek 💔, Weizmann Institute #AngewandteVIP #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

Striking Visual Demonstration: SpiroStrain by Cyclobutyl Accelerates Chemiexcitation. chemrxiv.org/engage/chemrxi…

"Deciphering the Role of the Ser-Phosphorylation Pattern on the DNA-Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis" Authors: Raj V. Nithun, Yumi Minyi Yao, Xiaoxi Lin, Shaimaa Habiballah, Ariel Afek, Muhammad Jbara onlinelibrary.wiley.com/doi/10.1002/an…

In the cover spotlight...🥳🎉

Excited to share our work that just appeared Angewandte Chemie. We introduce an orthogonal palladium(II) strategy to engineer complex modified proteins. We like transcription factors, so we demonstrated this approach in the preparation of 10 complex TF analogs onlinelibrary.wiley.com/doi/10.1002/an…

"Chemical Engineering of Artificial Transcription Factors by Orthogonal Palladium(II)-Mediated S-Arylation Reactions" Xiaoxi Lin, Omer Harel, Muhammad Jbara onlinelibrary.wiley.com/doi/full/10.10…

Thrilled to share my recent work now published in ACS Central Science !!! Many thanks to Muhammad Jbara, Ariel Afek 💔 and all co-authors. Site-Specific Acetylation of the Transcription Factor Protein Max Modulates Its DNA Binding Activity | ACS Central Science pubs.acs.org/doi/10.1021/ac…

A Versatile Method for Site-Specific Chemical Installation of Aromatic Posttranslational Modification Analogs into Proteins. Exciting collaboration with LashuelNeuroLab to decipher the role of aromatic PTMs in regulating α-Syn aggregation and pathogenicity. chemrxiv.org/engage/chemrxi…

Thrilled to share our latest work on the late-stage, site-specific chemical insertion of aromatic PTMs into proteins, published today in J. Am. Chem. Soc. A big thanks to LashuelNeuroLab for the exciting collaboration. Congratulations to Lin, Shaswati, and the team! pubs.acs.org/doi/10.1021/ja…

Had an incredible experience at the 37th European Peptide Symposium (EPS) and the 14th International Peptide Symposium (IPS). The event featured outstanding talks by renowned scientists around the world, and I enjoyed some of my best days in the beautiful city of Florence.✨

The FIRST chemiluminescent probe with a Turn-ON mechanism, utilizing a PeT mode-of-action. Insightful collaboration with Muhammad Jbara: Appearing today in ChemRxiv: chemrxiv.org/engage/chemrxi…

Happy to share our exciting collaborative work with the DYNAFLUORS group: We leveraged organometallic palladium chemistry for late-stage minimal labeling of peptides and proteins for real-time imaging of cellular trafficking. appeared today in: chemrxiv.org/engage/chemrxi…

Late-Stage Minimal Labeling of Peptides and Proteins for Real-Time Imaging of Cellular Trafficking | Published today in ACS Central Science Exciting collaborative work with the DYNAFLUORS group! Congratulations to Ferran Nadal-Bufi Nithun_Raj_V, and the rest of the team! pubs.acs.org/doi/10.1021/ac…

Delighted to share our new work now published in ACS Central Science🔥 Wonderful collaboration with Ferran Nadal-Bufi and DYNAFLUORS. Many thanks to Muhammad Jbara and all authors. pubs.acs.org/doi/10.1021/ac…

Checkout my recent work published in J Org Chem/Org Lett. Many thanks to Muhammad Jbara. One-Pot Total Synthesis of a Post-translationally Modified Max Transcription Factor Sheds Light on Ser-Phosphorylation and Lys-Acetylation Crosstalk in DNA Binding | Organic Letters pubs.acs.org/doi/10.1021/ac…

"One-Pot Total Synthesis of a Post-translationally Modified Max Transcription Factor Sheds Light on Ser-Phosphorylation and Lys-Acetylation Crosstalk in DNA Binding" Raj V. Nithun, Shada Khoury, and Muhammad Jbara pubs.acs.org/doi/10.1021/ac…

Truly honored to have been selected as a JSP Fellow at the 58th Bürgenstock Conference 2025. Thanks, Swiss Chemical Society and the organizers for an incredible and inspiring week in Brunnen! #SCS_BC25 bc25.scg.ch/jsp-program