Wagner S. Brum (@wagnersbrum) 's Twitter Profile
Wagner S. Brum

@wagnersbrum

MD-PhD student working with Alzheimer's disease biomarkers and their clinical interpretation at @goteborgsuni @ufrgsnoticias @zimmerneurolab

ID: 1025383450377957376

linkhttps://scholar.google.com/citations?hl=en&user=g0CSvU8AAAAJ calendar_today03-08-2018 14:10:40

1,1K Tweet

1,1K Followers

978 Following

Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

New paper alert: A two-cutoff CSF Aβ42/40 approach improves Aβ detection in real world clinical settings. CSF Aβ42/40≥7.1 rules out amyloid, while ratios~5.5–7.1 benefit from Aβ PET. Key for Lecanemab stratification. #Alzheimers #Biomarkers 📄 doi.org/10.1002/dad2.7…

Alexis Moscoso Rial (@alexismoscoso9) 's Twitter Profile Photo

Excited to share this collaborative work with Nicolas Villain / Moved to LinkedIn & BlueSky now published in Alzheimer's & Dementia. In this study, we reanalyzed the NACC neuropathologic data used in the 2024 Revised Criteria for the Diagnosis and Staging of Alzheimer’s Disease. alz-journals.onlinelibrary.wiley.com/doi/pdf/10.100…

Nico Franzmeier (@nfranzme) 's Twitter Profile Photo

Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP doi.org/10.1007/s00401…

Rafael Irizarry (@rafalab) 's Twitter Profile Photo

Biologists, stop putting UMAP plots in your papers! UMAP is a powerful tool for exploratory data analysis, but without a clear understanding of how it works, it can easily lead to confusion and misinterpretation. Link to Simply Statistics blogpost below.

Biologists, stop putting UMAP plots in your papers!

UMAP is a powerful tool for exploratory data analysis, but without a clear understanding of how it works, it can easily lead to confusion and misinterpretation.

Link to <a href="/simplystats/">Simply Statistics</a>  blogpost below.
Miguel Labrador-Espinosa (@mlabesp) 's Twitter Profile Photo

“Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology” from Nicholas Ashton, Wagner S. Brum & colleagues as the most read 2024 article in JAMA Neurology

Mychael Lourenco (@mvlourenco) 's Twitter Profile Photo

Happy to share this study led by Benedetta Bigio Carla Nasca lab NYU Langone Health and our team UFRJ just published molecularpsychiatry. Here, using two cohorts, we show that plasma carnitine levels are reduced in women with cognitive impairment and dementia. nature.com/articles/s4138…

Michael Schöll (@_michael_scholl) 's Twitter Profile Photo

Always my favourite post at the beginning of the year: Registration for our course “Biomarkers for neurodegenerative diseases” is now open! This year’s edition takes place at UCL Queen Square Institute of Neurology in central London on May 12-16. biomarker-course.org

Amit Kumar (@akumar_ki) 's Twitter Profile Photo

🚨 Open PhD Position 🚨 I am looking to hire a doctoral student for a fully funded PhD position focused on understanding the role of neuroinflammation and synaptic loss in Alzheimer’s disease and other proteinopathies with novel PET imaging biomarkers/kidoktorand.varbi.com/en/what:job/jo…

Zimmer Lab (@zimmerneurolab) 's Twitter Profile Photo

🚨 New Study just out in The Lancet Global Health 🧠 Lucas Da Ros, Wyllians Borelli, Cristiano Schaffer Aguzzoli & colleagues used a machine learning model to determine the most important risk factors for cognitive and functional decline in Brazil and other Latin American Countries 🧶1👇 thelancet.com/journals/langl…

Robert Howard (@profrobhoward) 's Twitter Profile Photo

Whatever we may think the Big Data or mouse studies show, only well conducted and adequately powered clinical trials can tell us whether repurposed drugs can help in neurodegenerative disorders. Most likely (in my view) they will not. If only it was so easy!

Jonathan Schott (@jmschott) 's Twitter Profile Photo

New *open access* paper in Alzheimer's & Dementia Journals — with the Alzheimer's Association #GBSC we compared 33 different plasma p-tau assays. TLDR — Plasma p-tau217 on several platforms was the best at discriminating Alzheimer’s from controls alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

New *open access* paper in <a href="/alzdemjournals/">Alzheimer's & Dementia Journals</a> — with the <a href="/alzassociation/">Alzheimer's Association</a> #GBSC we compared 33 different plasma p-tau assays. TLDR — Plasma p-tau217 on several platforms was the best at discriminating Alzheimer’s from controls  alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…
Nicholas Ashton (@nicholasashton) 's Twitter Profile Photo

and now the paper is out... pubmed.ncbi.nlm.nih.gov/39907496/ 📣 33 different ways to measure #blood #pTau 👉Mass Spec, semi & fully-auto immunoassays 🩸#pTau217 consistently best 📈Corr. between #pTau217 assays = optimism for standardisation Jonathan Schott Ashvini Keshavan Wagner S. Brum

Gemma Salvadó (@gesalbla) 's Twitter Profile Photo

Thrilled to be back home at Barcelonaβeta Brain Research Center as the Lead of the Neuroimaging Group! 🎉 Even better, we have a PhD position open to work with PET & MRI imaging in early stages of #Alzheimer’s. If you know someone passionate about neuroimaging, please share👇 barcelonabeta.org/es/centro-inve…

Zimmer Lab (@zimmerneurolab) 's Twitter Profile Photo

🎉 Congratulations to our PhD student Giovanna Carello-Collar for receiving the AAIC Neuroscience Next ‘One to Watch’ Award at #AAICNeuro 🇺🇸! A well-deserved recognition by the Alzheimer's Association for her contributions to neuroscience research. 👏✨

🎉 Congratulations to our PhD student <a href="/giovannacollar/">Giovanna Carello-Collar</a>  for receiving the AAIC Neuroscience Next ‘One to Watch’ Award at #AAICNeuro 🇺🇸!

A well-deserved recognition by the <a href="/alzassociation/">Alzheimer's Association</a> for her contributions to neuroscience research. 👏✨
Andrea L. Benedet (@andrealessa) 's Twitter Profile Photo

I am very honored to have my work recognized by the AAIC Neuroscience Next! Thank you to all my mentors, colleagues, and friends who have been incredibly supportive along the way. Alzheimer's Association Göteborgs universitet / University of Gothenburg

I am very honored to have my work recognized by the AAIC Neuroscience Next! Thank you to all my mentors, colleagues, and friends who have been incredibly supportive along the way.
<a href="/alzassociation/">Alzheimer's Association</a> 
<a href="/goteborgsuni/">Göteborgs universitet / University of Gothenburg</a>
Nicholas Ashton (@nicholasashton) 's Twitter Profile Photo

We're entering a new era of #Alzheimers blood testing—fully automated platforms now deliver fast, accurate #pTau217 results for use in primary & secondary care. Proud to share senior authorship and proud of this multi-centre European collaboration. 🔗 nature.com/articles/s4159…

Ilaria Pola (@ilaria_pola) 's Twitter Profile Photo

New paper out! We explored immune-related proteins in CSF and plasma in Alzheimer's disease, linking TSPO PET to neuroinflammation. Highlights: CXCL1 and TNFRSF11B in CSF show strong links to TSPO and AD pathways. Check it out! dx.doi.org/10.1002/alz.70…

Nicholas Ashton (@nicholasashton) 's Twitter Profile Photo

Fluid biomarker discovery in Alzheimer's and neurodegenerative diseases using Nucleic Acid Linked Immuno-Sandwich Assay AlamarBio Andrea L. Benedet alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Fluid biomarker discovery in Alzheimer's and neurodegenerative diseases using Nucleic Acid Linked Immuno-Sandwich Assay <a href="/AlamarBio/">AlamarBio</a> <a href="/andrealessa/">Andrea L. Benedet</a> 

alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…