Call for Abstract Extended Deadline for Cytokines 2024 / KAI 2024 - May 30, 2024 (23:59 KST)! For ICIS Student/Postdoc members the travel award application is also extended until May 30th #cytokines2024 Please retweet and plan to share your cytokine science at the joint meeting.

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

Great talk Juan L. Mendoza! Having a great time in Seoul and thank you to ICIS 🦋 @cytokinesociety.bsky.social for the generous Travel Award allowing me to present my work here!

Great story and great technology from Adam Broerman, Institute for Protein Design, and others. Excited to apply this to the next generation of cytokine therapeutics! #proteindesign

We are all born with a genetic lottery. Millions of T cell receptors are what we have with a hope to defend all cancer and viruses. What if that's not enough? Hope our work can give an interesting answer to you. biorxiv.org/content/10.110…

🚨 New Episode of In Translation 🚨 Great sitting down with Jef Boeke and Cholpisit Ice Kiattisewee to talk synthetic genomics! Hope you enjoy!

I’m excited to share William Grubbe paper was just published. He was relentless and methodical. Thank you to all our authors and collaborators at UChicago: Bixia, Minglei, Engin at the NIH: Jake and team. Special thanks to Mila ProkuninaOlsson nature.com/articles/s4146…

What is needed to accelerate enzyme engineering using machine learning? #Data We develop a ML-guided platform that integrates DNA assembly, gene expression, and functional assays. ML models predict improved variants. Ashty Karim Northwestern CSB Nature Communications nature.com/articles/s4146…

Thank you UChicago Pritzker Molecular Engineering for this great write up covering our new story! pme.uchicago.edu/news/protein-e…

#UChicagoPME researchers in the Juan L. Mendoza Group have developed a method to produce an immune protein to facilitate future studies on why it makes immune responses worse. 📰pme.uchicago.edu/news/protein-e…

Grateful to have our work featured by the editors!

Fantastic work coming out of Juan L. Mendoza lab recently! Structural and signaling dynamics of an interesting cytokine in the interferon family, IFNL4, thanks to a breakthrough that allowed the team to express the protein in high quantity and purity. nature.com/articles/s4146…

Congratulations to the new graduates of UChicago Pritzker Molecular Engineering !!

I am happy to share that we have a great opportunity for a postdoctoral scientist. Please share. hhmi.wd1.myworkdayjobs.com/en-US/External…

We sought to make proteins both potent and FAST. We used #proteindesign to design precise control over protein interaction lifetimes, enabling us to construct rapid-response circuits, biosensors, and switchable cytokines. Now published nature! Links to paper and tutorial below.

Scientists have designed an interleukin-21 mimic with increased stability and capacity to induce more potent #antitumor activity than the native protein, which could inform improved #immunotherapies. Institute for Protein Design Learn more in Science #Immunology: scim.ag/3KsvCy9

A new Science #Immunology study describes a potent interleukin-21 mimic that can stimulate cytotoxic T cells and shows strong #antitumor activity in mouse models of cancer and in tumor explants derived from patients with #melanoma. scim.ag/3KsvCy9

🤯🤯 A Paper from David Baker labs is here!!👇 Can we control immune cell behavior by precisely tuning how cytokine receptors are positioned in space relative to each other?Institute for Protein Design bioRxiv "Geometric Tuning of Cytokine Receptor Association Modulates Synthetic