𝕨𝕚𝕝𝕝 𝕚𝕟𝕔𝕖 (@will_oncology) 's Twitter Profile
𝕨𝕚𝕝𝕝 𝕚𝕟𝕔𝕖

@will_oncology

oncologist | genitourinary (renal-prostate-bladder) head & neck | interested in clinical trials/biomarkers/immunotherapy | Addenbrooke’s, Cambridge; from 🇯🇪

ID: 1509956623191707653

calendar_today01-04-2022 18:11:32

383 Tweet

313 Followers

698 Following

Tom Powles (@tompowles1) 's Twitter Profile Photo

NIAGRA: neoadjuvant gem/cis +/- perioperative durvalumab shows significant OS and EFS. #GU25 Matt Galsky now shows the prognostic relevance of pCR. It also showed the durvalumab outperforms the control arm irrespective of pCR. OncoAlert

NIAGRA: neoadjuvant gem/cis +/- perioperative durvalumab shows significant OS and EFS. #GU25 <a href="/MattGalsky/">Matt Galsky</a> now shows the prognostic relevance of pCR. It also showed the durvalumab outperforms the control arm irrespective of pCR. <a href="/OncoAlert/">OncoAlert</a>
Enrique Grande (@drenriquegrande) 's Twitter Profile Photo

I love being provocative and I love to see people provocative at the stage. For me, it makes us to come out the comfort zone and think beyond. What a lovely conclusion from Elizabeth Plimack MD in her terrific discussion of perioperative treatment of MIBC at ASCO #GU25. It merits to

I love being provocative and I love to see people provocative at the stage. For me, it makes us to come out the comfort zone and think beyond. What a lovely conclusion from <a href="/ERPlimackMD/">Elizabeth Plimack MD</a> in her terrific discussion of perioperative treatment of MIBC at <a href="/ASCO/">ASCO</a> #GU25. 
It merits to
Toni Choueiri, MD (@drchoueiri) 's Twitter Profile Photo

Our very own Wenxin (Vincent) Xu taking the stage to discuss his outstanding work on KIM-1 as a biomarker of response to immunotherapy in #RCC High baseline KIM-1 = Worse outcomes Early KIM-1 drop on NIVO+IPI = Major survival benefit 3-week >30% decrease ➡️ ORR 69%, mPFS 71 mo, mOS

Our very own <a href="/VincentWenxinXu/">Wenxin (Vincent) Xu</a> taking the stage to discuss his outstanding work on KIM-1 as a biomarker of response to immunotherapy in #RCC
High baseline KIM-1 = Worse outcomes
Early KIM-1 drop on NIVO+IPI = Major survival benefit
3-week &gt;30% decrease ➡️ ORR 69%, mPFS 71 mo, mOS
LARVOL (@larvol) 's Twitter Profile Photo

Trending 10 key trials among oncologists on X following ASCO-GU 2025, spotlighted by LARVOL CLIN. #LARVOL #GU25 #Oncology #CancerResearch #CancerData #GUCancer #GenitourinaryOncology #ClinicalTrials

Trending 10 key trials among oncologists on X following <a href="/ASCO/">ASCO</a>-GU 2025, spotlighted by <a href="/Larvol/">LARVOL</a> CLIN.

#LARVOL #GU25 #Oncology #CancerResearch #CancerData #GUCancer #GenitourinaryOncology #ClinicalTrials
Nicholas Zaorsky, MD MS (@nicholaszaorsky) 's Twitter Profile Photo

Guiding Treatment for Patients With Prostate Cancer With Biochemical Recurrence After Prostatectomy dailynews.ascopubs.org/do/guiding-tre… with Amar Kishan Daniel E Spratt Thanks ASCO Daily News Related Nature Reviews Urology article: pubmed.ncbi.nlm.nih.gov/34363040/ x.com/NicholasZaorsk…

Guiding Treatment for Patients With Prostate Cancer With Biochemical Recurrence After Prostatectomy
dailynews.ascopubs.org/do/guiding-tre…
with <a href="/AmarUKishan/">Amar Kishan</a> <a href="/DrSpratticus/">Daniel E Spratt</a> 

Thanks <a href="/ASCO/">ASCO</a> Daily News

Related <a href="/NatRevUrol/">Nature Reviews Urology</a> article: pubmed.ncbi.nlm.nih.gov/34363040/
x.com/NicholasZaorsk…
Tom Powles (@tompowles1) 's Twitter Profile Photo

NIAGARA’s surgical safety results #EAU25 with Jim Catto. Results show the addition of duvalumab to neoadjuvant platinum chemotherapy did not increase surgical complications or cystectomy rates.

NIAGARA’s surgical safety results #EAU25 with Jim Catto. Results show the addition of duvalumab to neoadjuvant platinum chemotherapy did not increase surgical complications or cystectomy rates.
John McGrane (@mcgranjo777) 's Twitter Profile Photo

Great to see this guy at Leeds when discussing 👍#kidneycancer. Unfortunately I was a definite last place in the Enrique Grande lookalike competition that Naveen Vasudev won last year !!!

Great to see this guy at Leeds when discussing 👍#kidneycancer.
Unfortunately I was a definite last place in the <a href="/drenriquegrande/">Enrique Grande</a> lookalike competition that <a href="/nav_vasudev/">Naveen Vasudev</a>  won last year !!!
Javier Gavira (@jgavirad) 's Twitter Profile Photo

🚀 New study published in #EJC! This 🇪🇺 retrospective study evaluated the activity of #lenvatinib in 133 previously treated patients with metastatic #RCC #kidneycancer. 🔗sciencedirect.com/science/articl… OncoDaily UroToday.com GU Oncology Now OncoAlert

Katy Beckermann (@katy_beckermann) 's Twitter Profile Photo

📄 New analysis from the TITAN trial: 🔍 In mCSPC patients treated with apalutamide: • 🧬 Discordant progression occurred in 52.2% of patients (60 of 115) in the apalutamide group and 27.5% (58 of 211) in the placebo group (p < 0.001) 📢 Takeaway: PSA alone isn’t enough—routine

Laurence Albiges (@albigesl) 's Twitter Profile Photo

Day 1 ESMO - Eur. Oncology #Preceptorship in Metastatic #urothelial #RCC #cancer 62 participants from 26 countries selected out of >230 applicants ! Thanks to the faculty for sharing #SOC ESMO - Eur. Oncology #guidelines

Day 1 <a href="/myESMO/">ESMO - Eur. Oncology</a> #Preceptorship in Metastatic #urothelial #RCC #cancer 
62 participants from 26 countries selected out of  &gt;230 applicants ! Thanks to the faculty  for sharing #SOC <a href="/myESMO/">ESMO - Eur. Oncology</a> #guidelines
Raffaele Colombo (@raffcolo) 's Twitter Profile Photo

sacituzumab govitecan (SG) vs sacituzumab tirumotecan (Sac-TMT) = antibody ≈ DAR (7.6 vs 7.4) ≠ conjugation chemistry (maleimide vs pyrimidine) ≈ linker (except conjugation part) = carbonate cleavable group ≠ payload structure and properties (SN-38 vs KL610023)

sacituzumab govitecan (SG) 
vs 
sacituzumab tirumotecan (Sac-TMT)

= antibody 
≈ DAR (7.6 vs 7.4)
≠ conjugation chemistry (maleimide vs pyrimidine)
≈ linker (except conjugation part) 
= carbonate cleavable group 
≠ payload structure and properties (SN-38 vs KL610023)
UroToday.com (@urotoday) 's Twitter Profile Photo

Treatment patterns and survival outcomes before and after access to immune checkpoint inhibitors for patients with metastatic #UrothelialCarcinoma: a single-center retrospective study from 2004 to 2021. Author commentary on UroToday > bit.ly/40Lmbye Jose C. Tapia

Treatment patterns and survival outcomes before and after access to immune checkpoint inhibitors for patients with metastatic #UrothelialCarcinoma: a single-center retrospective study from 2004 to 2021. Author commentary on UroToday &gt; bit.ly/40Lmbye <a href="/TapiaJC1/">Jose C. Tapia</a>
HemOnc Today (@hemonctoday) 's Twitter Profile Photo

All patients who received a personalized #vaccine for advanced #kidneycancer achieved an immune response, according to results of a phase 1 trial. Healio spoke with David Braun of Yale School of Medicine and Yale Cancer Center about the data and its implications. 🔗Read here bit.ly/3QJDSd6