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Cells sense their environment better by measuring longer - but what if the environment changes? We take a simple model of a cell sensing chemicals secreted by moving bacteria, and show how the cell's optimal behavior depends on bacterial density + dynamics arxiv.org/abs/2310.00062

Cell-cell contact can lead to one cell repolarizing and moving away from contact - even if the contact area is tiny. When could a cell get confused about whether another cell is touching it? Preprint from Wei Wang in our group! arxiv.org/abs/2311.00085

Our work on how a cell can best sense a dynamically-changing chemical signal - and what sort of environments can lead to a rapidly-changing signal - is now out in Biophys. J: authors.elsevier.com/a/1i%7EbF1SPT7… .

Limits on the accuracy of contact inhibition of locomotion, Wei Wang (汪巍) and Brian A. Camley #Cells #BiologicalPhysics Brian Camley Wei Wang (汪巍) go.aps.org/3UN5oYS

Thanks to Physical Review E for highlighting Wei Wang (汪巍) 's work on how precisely cells can sense cell-cell contact - out now!

Phys. Rev. E 109, 054408 (2024) - Limits on the accuracy of contact inhibition of locomotion journals.aps.org/pre/abstract/1…

Trade-offs in concentration sensing in dynamic environments: Biophysical Journal cell.com/biophysj/fullt…

New study explores how cells navigate changing environments by sensing chemicals. Kashyap et al. model a single eukaryotic cell sensing bacteria-secreted chemicals to reveal how the noise to environmental variation ratio dictates sensing accuracy. ow.ly/ZciZ50RP9u3

Work by Aparajita Kashyap, Wei Wang, and me - out now in Biophysical Journal!

Confinement, jamming, and adhesion in cancer cells dissociating from a collectively invading strand biorxiv.org/cgi/content/sh… #biorxiv_cellbio

Confinement, jamming, and adhesion in cancer cells dissociating from a collectively invading strand biorxiv.org/content/10.110…

What controls whether cells - or clusters of cells - break off from an invading cancerous front? New preprint from my group in collaboration with the Konstantopoulos group Konstantopoulos Lab , led by Wei Wang (汪巍) doi.org/10.1101/2024.0…

Black Myth: Wukong has sold 10 million copies across all platforms. (Data as of 21:00 Beijing time, August 23, 2024) Thanks to all players worldwide for your support and love. Have a great gaming weekend! #BlackMythWukong

Google Scholar Blog:AI outlines in Scholar PDF Reader: skim per-section bullets, deep read what you need scholar.googleblog.com/2024/11/ai-out… via @google

Simulations of cancer cell invasion reproduce experiments in microfluidic channels, showing how confinement, adhesion, and chemotaxis affect how cells break off from an invading front and rupture — behavior that can lead to #metastasis. Read the paper: go.aps.org/41xXR4N

Check out our latest preprint on arXiv! 🥳 Controlling tissue size by active fracture arxiv.org/abs/2503.03126

A phase field model of cancer cell invasion explores how confinement, adhesion, and chemotaxis drive cell dissociation that can lead to #metastasis — capturing cell behavior observed in experiments with microfluidic channels. Read the paper: go.aps.org/41xXR4N

Groups of cells can both grow and break apart. What physical factors control these fractures? What sets the eventual size of clusters? Read our paper: arxiv.org/abs/2503.03126