🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Chromatin folks: don't miss GRC/GRS Genome Architecture in Cell Fate and Disease, June 15-20 2025 Ventura, CA. Registration deadline: Mar 18, 2025. grc.org/genome-archite…

De-novo DNA Methylation of Bivalent Promoters Induces Gene Activation through PRC2 Displacement biorxiv.org/content/10.110… #biorxiv_genomic

You are never too senior to work hard & get yourself a nice first author Science paper! 👏🏻👏🏻👏🏻 science.org/doi/10.1126/sc…

Less than one month away from abstract submission deadline for the 2025 GRC/GRS Genome Architecture meeting at the beautiful beach in California. Don't miss it!

Construction of an atlas of transcription factor binding during mouse development identifies popular regulatory regions Read this Techniques & Resources Article by Anna Nordin, Gianluca Zambanini, Mattias E. Jonasson, Pierfrancesco Pagella Claudio Cantù & co.: doi.org/10.1242/dev.20…

Congratulations to Bing!!

Excited to share our pre-print on the molecular architecture of heterochromatin in human cells🧬🔬 w/ Jan Philipp Kreysing, Johannes Betz,Turoňová lab, Marina Lusic, Hummer lab, Beck Laboratory, Max Planck Institute of Biophysics 🔗 Preprint here: doi.org/10.1101/2025.0…

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

Super interesting finding on marsupial. Congratulations to James Turner and the team!

I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in Science Magazine ! (link at end of 🧵)

very cool.. nature.com/articles/s4158… Conservation of regulatory elements with highly diverged sequences across large evolutionary distances

An atlas of transcription factor-driven gene programs across human cells Teichlab biorxiv.org/content/10.110…

Our new paper is finally out, uncovering the distribution of H2A variants in mouse oocytes and the epistasis between H2A.Z and H3K4me3 across intergenic regions. nature.com/articles/s4159… Short summary in thread↓↓ (1/9)

Many active histone modifications accumulate upon ZGA in non-mammalian vertebrates, but are they truly required for proper ZGA? In our new paper, we propose a model of their functions during ZGA in teleosts. Please check it out! doi.org/10.1038/s41467…

The Cold Spring Harbor Asia (CSHA) meeting - Nuclear Architecture and Function is coming up soon! (Sept 1-5, 2025). Abstract submission deadline extended to July 18. Fantastic speakers & beautiful city (Suzhou) with Royal Garden. Check out here: csh-asia.org/?content/2743

Online now: Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free condition dlvr.it/TLf6wf