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Love this approach Xin Zhou Lab Transferrin receptor targeting chimeras for membrane protein degradation | Nature nature.com/articles/s4158…

Congratulation on a beautiful paper Xin Zhou Lab!!!

Can we recruit transcriptional kinases to activate gene expression? New in @sciencemagazine my first postdoc work developing CDK-TCIPs, a new inducer of proximity. We wondered if P-TEFb could be redirected to activate genes of interest. science.org/doi/10.1126/sc… . #ScienceResearch

Xin Zhou, PhD, a researcher at Dana-Farber and her team have developed a new platform that repurposes a cancer cell's own refueling mechanism to degrade proteins driving tumor growth. This breakthrough could reshape how we approach cancer treatment. blog.dana-farber.org/insight/2024/1…

One of my newest adventures - hosting a podcast! If you are keen on chemical biology, medicinal chemistry, chemical probes, tool compounds, degraders, chemoproteomic tools, and more... tune to @Target2035 podcasts. Pilot episode is out... more to come! podcasters.spotify.com/pod/show/targe…

We absolutely loved seeing this video explaining our TransTAC technology for targeted membrane protein degradation!! Hoping TransTAC opens doors to new cancer therapies and more!

1/3 Today, an anecdote shared by an invited speaker at #NeurIPS2024 left many Chinese scholars, myself included, feeling uncomfortable. As a community, I believe we should take a moment to reflect on why such remarks in public discourse can be offensive and harmful.

New from the Brian Liau Lab, two papers in nature that reveal a chemical-genetic convergence #chemtwitter #CancerResearch