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We demonstrate how OLS imaging enables, large scale, robust and sensitive measurements of protein dynamics in live cells and in solution. Great collaborative effort! Eikon Therapeutics #microscopy biorxiv.org/content/10.110…

Eikon has come a long way in just four years, and SMT has proved a far more powerful tool for understanding intracellular protein interactions and optimizing drug development than I ever imagined. youtu.be/mLA6qRfqZJ0?fe… via YouTube

AI alignment tasks often have access to a reward model, but existing alignment approaches do not incorporate the reward model (DPO) or are computationally involved (RLHF). We present Energy Rank Alignment, which incorporates a reward model using a simple objective (with no RL!).

If you’d like to learn more about how Eikon Therapeutics is applying oblique line scan imaging to generate robust single molecule tracking datasets in live cells and in solution stop by poster 25P-250 this afternoon. #IUPAB2024

Mind-blowing movies of biomolecules in action at 100 fps and 1-nm resolution #IUPAB2024 High-speed AFM is just *fantastic* 🤯🔝

what a privilege to meet so many cool and brilliant scientists! #IUPAB2024 Amine Driouchi Yugo Inutsuka

#IUPAB2024 was so great! Amine Driouchi Luciano A. Masullo Yugo Inutsuka Elizabeth Hinde

Thanks a lot Yugo Inutsuka and Takanobu A Katoh for showing me some of the advanced microscopy projects you’re working on and for all the hospitality! 東京大学 | UTokyo! Truly world class work!

Japan 🇯🇵, a land of tradition, technological innovation and surprises! Thanks @iupab2024_kyoto for organizing a memorable conference!

UCT UCT IDM

Introducing PetaKit5D: a comprehensive suite of software tools for processing petabyte-scale microscopy data from Janelia Sr Fellow/HHMI Investigator Eric Betzig, Xiongtao Ruan, Matthew Mueller, Srigokul Upadhyayula Advanced Bioimaging Center @ UC Berkeley UC Berkeley & colleagues nature.com/articles/s4159…

Huge congratulations to our BME faculty and innovative leader in Biological Fluorescence/Biophotonics Professor Enrico Gratton for being honored as a Biophysical Society Fellow! #uci #bps2025 UC Irvine BME UCI Engineering Biophysical Society

Excited to share our newest publication from work conducted at Eikon Therapeutics . nature.com/articles/s4159… With oblique line scan (OLS), and using single molecule tracking (SMT), you can sample the baseline heterogeneity of your biological system of interest with exquisite resolution.

Thanks to Eric Betzig for the initial proof of concept and continuous support.

Out today from the Anderson lab, Oblique line scan microscopy achieves nanoscale spatial and sub-millisecond temporal resolution across a large FOV, enabling robust single-molecule biophysical measurements and tracking in both cells and solution. nature.com/articles/s4159…

Eikon Therapeutics is making waves in the scientific community with their groundbreaking Oblique Line Scan Technology, as featured in Nature Methods! Check out the full announcement here: businesswire.com/news/home/2025… #EikonTherapeutics #Innovation #trynectarfree

Correlative Microscopy across biological scales at its finest. Great work Eric and team!