I am proud of Marlon V. Duro and Juno Van Valkenburgh and thankful to @kaichen_USC for publishing the method for making 18-F DHA for the first time. This tool will ultimately help us study the effects of APOE4 on brain DHA metabolism in humans pubs.acs.org/doi/10.1021/ac…

Happy Holidays! Fun to work with a great and diverse team.

Slavoj Žižek posits: "Why wish to be happy when you could be interesting?". May 2024 bring us interesting and curious discoveries!

Our last paper of 2023 (or first of 2024) is out! Together with Yassine Lab and Wade Self we discussed #microbiome's effect on #omega3 supplementation in improving cognition, specifically in #Alzheimers disease. journals.lww.com/co-clinicalnut…

📣🎉Congrats to PhD student, Koral Wheeler, who led our new review article in the Journal of Alzheimer's Disease: "Using Neuroimaging to Study Cerebral Amyloid Angiopathy and Its Relationship to Alzheimer's Disease" 💻🧠🩸 pubmed.ncbi.nlm.nih.gov/38306032/ Irimia Lab

How do vegetarians compensate for lower intake of DHA or EPA in their diets? Bilal Kerman Wade Self and I hypothesize that clues to this question are in the gut microbiome. Excited to collaborate with the Alzheimer's Gut Microbiome Project #Alzheimers journals.lww.com/co-clinicalnut…

It was an honor to co-chair the scientific session Alzheimer's Association on Recruitment of Latino/a/e/x Participants to Research and Clinical Trials with Dr. Maria Aranda. #AlzLatinos2024

How does the brain metabolism of the omega-3 DHA change across the lifespan in individuals carrying the APOE4 allele? Credit to the talented Brandon Ebright for leading this review. Keck School of Medicine of USC , #USCMann, #Alzheimers , #APOE4 sciencedirect.com/science/articl…

We are honored to have the new USC Center for Personalized Brain Health featured in Science. keck.usc.edu/cpbh/about/ science.org/content/articl….

I pray for peace for all my friends and family in the Middle East. What keeps us together is far more than what drives us apart.

In this work, our talented PhD student Boyang Li analyzes complex data sets to identify signatures of cholesterol metabolism as key drivers of microglial cellular senescence in AD: biorxiv.org/content/10.110…

How do brain lipids influence the development of cellular senescence in the brain? We propose the over-activation of cPLA2 as a key driver of oxidized lipids and senescence and introduce the application of V-SYNTHES to develop potent cPLA2 inhibitors: liebertpub.com/doi/pdf/10.108…

In a systematic review, we find little evidence for omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on cognition in a general population: content.iospress.com/articles/journ…

A connection between Alzheimer’s and cholesterol? 🧪 Researcher Hussein Yassine, MD, USC Center For Personalized Brain Health, discovered a link between #Alzheimer's disease and issues with cell function and cholesterol in the brain, potentially opening new pathways for treatment. bit.ly/4hRXGXf