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Thrilled to share our new preprint @XiaoWan38018817: in situ electro-seq that integrates soft bioelectronics, in situ sequencing, and machine learning to chart stem cell electrophysiology and gene expression at single cell resolution across time and space biorxiv.org/content/10.110…

Cool work led by Jia Liu and @XiaoWan38018817 -Thank you for incredible support and guidance. Thanks to asdqwr as a great collaborator. Thanks to every co-author and every member in Liu Lab and Wang Lab👏🏻

Our company, Axoft, is building a scalable platform for implantable brain-machine interfaces. We are looking for electrical/system engineer, nanofabrication engineer, and brain surgical technicians. Please RT and contact us if you are interested! axoft.us/careers

Happy to share our spatial atlas of the mouse central nervous system at molecular resolution using STARmap PLUS method and ClusterMap (rdcu.be/cWLg4) pipeline led by Hailing Shi, Yichun He, Yiming Zhou in collaboration with Jia Liu. biorxiv.org/content/10.110…

Excited to share TEMPOmap, our new spatiotemporal transcriptomics method that integrates metabolic labeling with 3D in situ sequencing to simultaneously profile the age and location of individual RNA molecules led by Rena Ren Haowen Zhou and Hu Zeng biorxiv.org/content/10.110…

Thrilled to share RIBOmap, a 3D in situ profiling method to detect mRNA translation for thousands of genes simultaneously in the context of subcellular architecture, cell types, and tissue anatomy led by Hu Zeng Jiahao Huang Rena Ren biorxiv.org/content/10.110…

Beyond excited and proud! Grateful for leading this project with my wonderful colleagues Yichun He Yiming Zhou under the guidance of Xiao and Jia Jia Liu! Thanks to every coauthor and all members in Xiao Wang💪 Spatial molecular atlas of the mouse brain and more

Stunning preprint from Xiao Wang and Jia Liu introducing STARmap PLUS for in-situ transcriptome profiling. Used to generate a 3D map of the whole mouse brain and spinal cord (1,000 genes, 1M+ cells) biorxiv.org/content/10.110…

Huge congrats to Hailing and the whole team, and thanks so much for the suggestions and help from the editor, reviewers, and colleagues through the long journey! Spatial atlas of the mouse central nervous system at molecular resolution: rdcu.be/dnaYu

Excited to share Deep-STARmap and Deep-RIBOmap! We enabled spatial transcriptomic and translatomic mapping of >1K genes in 200 µm thick tissue and neuron morphology co-profiling. Thanks Xiao Wang for unwavering support; Jennifer for human skin study! biorxiv.org/content/10.110…

Check our work on Fine-Tuning Discrete Diffusion Models!

Happy to share AutoSort, an end-to-end deep neural network for real-time tracking & decoding of single neurons! We revealed neural manifold drift, stabilization, & post-learning drift in monthslong motor task. Thanks Jia Liu for unwavering support!

Check our work on an autonomous AI agent for spike sorting!

Thrilled to share our latest preprint regarding STAgent, a multimodal AI agent for spatial transcriptomics.: (1/9) Check our manuscript at: biorxiv.org/content/10.110… and demo at: youtu.be/aEUop05RINY

Researchers have created a thin, stretchable device that can be implanted into a tadpole embryo’s neural plate, the early-stage, flat structure that folds to become the brain and spinal cord. The device records electrical activity from single brain cells. bit.ly/4dR00wM

Check out our great work just published in Nature! We implanted ultrasoft, stretchable electronics into the brain by letting the brain grow around them from the earliest stages of development. 🎉 Proud of the team and excited to share these findings!