🧠 Which brain cell types are connected, and what do those connections look like? 🤔 Recording from multiple live neurons simultaneously — our researchers mapped thousands of cortical connections to find out. 🧵 1 alleninstitute.org/what-we-do/bra…

A must-go meeting!

Microglia-mediated degradation of perineuronal nets promotes pain (today❤️‍🔥) science.org/doi/10.1126/sc…

Hard to transfect microglia in vivo? Here comes a solution published in Nature Method today: AAV-cMG and AAV-MG variants efficiently deliver various genetic payloads into microglia without inducing microglial immune activation. nature.com/articles/s4159…

Absolutely love this tweet, and as an editor, I really appreciate S. videos that are walk throughs of a software GUI on test data.

Very good practice.

Molecular basis of astrocyte diversity and morphology across the CNS in health and disease science.org/doi/10.1126/sc…

Neurons and astrocytes closely coordinate their gene expression, in a program we call “SNAP” – a collaboration that we find to be central in protection from schizophrenia and cognitive aging. nature.com/articles/s4158…

Congratulations to lead author Michelle Cahill, Max Collard, @vincenttse, and team for this work on how astrocytes respond to glutamate and GABA, the two major neurotransmitters in the brain. 🎉 nature.com/articles/s4158…

AQuA2 is released. A fast, accurate, and versatile data analysis platform. Try it if you have imaging activity data. Designed for various biosensors, cell types, and imaging modalities. Powerful to extract the dynamic features in both space and time. biorxiv.org/content/10.110…

Excited to announce that a part of my thesis work with Misha Ahrens and Florian Engert is out on bioRxiv! Summary 🧵⬇️, but first let me shout out this incredible companion piece by @LeftonKatie with Thomas Papouin (Papouin Lab - WashU)

Online now: An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination dlvr.it/T7chfB

Excited to share our work on data science in large neuroscience collaboration published in Neuron. We found some challenges but also opportunities on data integration, sharing and research training. Hope it paves the way for further advancing the field. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

Please RT: We are hiring! Apply to join the exciting research going on Duke Department of Cell Biology! jobs.sciencecareers.org/job/662805/fac…

Hot preprint alert!!! Please check out our study led by the amazing Pia Rodriguez on how mitochondrial fission regulates astrocyte morphogenesis! Unexpected findings linking astrocyte mitochondria to tiling and gap junction coupling!!! biorxiv.org/content/10.110…

This preprint also features a new computational method, Seg_Astro, developed by our collaborators Boyu Lyu and Yu Lab @ Tsinghua to analyze astrocyte branching.

Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals: Cell cell.com/cell/fulltext/… AQuA2, the analysis platform was tested for various application scenarios.

My lab at Tsinghua University, China, has multiple openings for graduate students and postdoctoral fellows. Our research focuses on developing models, algorithms and tools to analyze and quantify biological imaging and omics data. Feel free to email me at [email protected]