🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🌟Join the Xiao Lab University of Michigan🌟Recruiting PhD students and postdocs in spatial biology 💡🧲 We're seeking both experimental and/or computational individuals with a passion for the interdisciplinary research of omics, bioengineering, and pathology. More info: xiaoyang.nyc/join

Thank you, Arutha K, for inviting me to speak at MultiOmics 2024 and welcoming me into the Spatial Jedi community! Honored to connect with leaders in the field and update my knowledge of cutting-edge technologies. #MultiOmics2024 #SpatialBiology

Excited to share our lab's first preprint: we used spatial transcriptomics to dissect how aging disrupts the cycling ovary! 🧵 This was an incredible team effort w/ Jennifer Garrison Tammy Lan David Fischer AlisonKochersberger Ruth Raichur Sophia Szady

Wanna do same slide spatial multi-omics? Check out our new approach, IN-DEPTH, compatible with multiple spatial proteomics and transcriptomics platforms to uncover new biological insights for tumor viruses and the TME! Led by YaoYu Yeo Yuzhou Chang Huaying Qin Ma BMBL

🧬 Exciting New #SpatialAnalysis Tool! 🧬 🚀 Introducing PRISM: A powerful Python package for the interactive and integrated analysis of multiplexed tissue microarrays! biorxiv.org/content/10.110…

Congrats to my postdoctoral mentor, Garry P. Nolan , on receiving the Arthur Kornberg and Paul Berg Lifetime Achievement Award in Biomedical Sciences! Honored to be under Papa Garry's tutelage and learn how to empower others to do impactful science. youtube.com/watch?v=dvj4kx…

Thank you Yale Cancer Center Center for the highlight! The immense resources provided by your center is critical to our progress. Thank you for all the great support!

Fantastic work led by Alexandros Drainas, Xavier Rovira Clavé, Julien Sage, and Garry P. Nolan advancing antibody testing technology to achieve the throughput needed to address public health challenges for infectious diseases and monitor personal immunity. nature.com/articles/s4155…

Looking forward to being back at Stanford University !

Welcome back ~~

Thanks to Nils Gehlenborg for the invitation to speak—it was fantastic catching up with others who share a passion for 3D tissue maps!

Always a pleasure working with such a talented team—thrilled to see our work published in Nature Genetics today! For people interested in understanding their tissue's state deeper, try our new tool MESA!

🎉We are excited to share that our newest spatial method, SM3DD! This is a cell segmentation /annotation-free approach for interpreting 3D Spatial Transcriptomics. Preprint available here: biorxiv.org/content/10.110… 1/11

1⃣Small panels in #CODEX, #Xenium & #CosMx make fine cell typing tough. Our collab with Bokai Zhu , Sizun Jiang & Garry P. Nolan brings #CellLENS! Published today in Nature Immunology: nature.com/articles/s4159….

👉📣Introducing KRONOS, a panel-agnostic foundation model purpose-built for multiplex spatial proteomics! Access the pre-print here: arxiv.org/pdf/2506.03373 Trained self-supervised on 47 million single-marker patches spanning 175 protein markers, 16 tissue types, 8 imaging

Chuffed to share KRONOS: A foundation model for Spatial Proteomics! arxiv.org/abs/2506.03373 Exciting work with the indomitable Faisal Mahmood, led by the amazing Muhammad Shaban, Yuzhou Chang, with Huaying, YaoYu Yeo, Guillaume Jaume, Andrew Song, and our collaborators

🧵 Highlights from our study on Merkel Cell Carcinoma: 📍 8M cells, 60-patient spatial atlas 🦠 Virus(+) vs virus(–) MCC spatial features 🔥 CXCL9⁺ DCs–CXCR3⁺ CD8 T cell niche in virus(+) MCC 🧬 Confirmed in HPV⁺ oropharyngeal cancer 🎯 Biomarkers for metastasis & ICB response

Grateful to be selected for the Arthur & Sandra Irving Cancer Immunology Symposium! Learned from leading cancer immunology experts on lab leadership: founding, funding, mentoring & impactful vision, and connected with 45 brilliant peers. Excited for what’s ahead! #IrvingSymposium

Are you trying to build a so-called AI virtual cell? 🔬 Yet ... the mean still outperforms your perturbation-response prediction model. 😮‍💨 Our paper— just accepted to the 𝗚𝗲𝗻𝗕𝗶𝗼 𝗪𝗼𝗿𝗸𝘀𝗵𝗼𝗽 @ 𝗜𝗖𝗠𝗟 —dives into 𝘸𝘩𝘺 the mean excels and what you can do about it.

We have reduced the footprint and concentrated the science this year! One day event - in person, zoom, and posters...