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Test-time scaling has arrived for biological design. Excited to share new work from Nabla Bio. By scaling test-time compute, we've achieved remarkable leaps in de novo antibody design against difficult drug targets.

This. Would repost this 1000x if I could. Most people don't realize the scale of what's going on Thousands of promising scientists whose careers have come to a grinding halt, all scared to speak out because it might jeopardize our next job, immigration status, etc.

it'd be kinda funny if it wasn't true

Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in nature. This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at Centre for Genomic Regulation (CRG) nature.com/articles/s4158…

A new combination technique enables DNA sequencing and high-resolution imaging in intact cells — offering new insights into progeria and aging. broad.io/expansion-in-s… Jason Buenrostro Fei Chen Lab Ajay Labade Caroline Comenho zack chiang Science Magazine

Thrilled to announce that our work on Expansion In Situ Genome Sequencing (ExIGS) is now published in Science Magazine! ExIGS allows us to sequence DNA and image proteins with super-resolution directly within single cells. science.org/doi/10.1126/sc…

Super excited that Expansion In Situ Genome Sequencing (ExIGS) is out now in Science Magazine ! Check out the paper to see what can be revealed by sequencing the genome in its native position and high-res imaging its interactions with nearby proteins. science.org/doi/10.1126/sc…

can someone please train a deep learning weather model to explain why it rains every freakin' weekend in boston

really enjoyed this essay, it captures a lot of the issues that broadly plague science and puts them in simple terms these issues are only amplified in biology where the timescales are far longer and the rewards less evenly distributed