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Study on the function of mouse pachytene piRNAs from Dean Lab: Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA biorxiv.org/content/10.110…

We are hiring for multiple positions: Postdoctoral Researchers, an Executive Assistant to the Chair, and a Research Laboratory Technician. Information on how and where to apply can be found on our lab website: zamorelab.umassmed.edu/availableposit…

There are only 18 days left to register for the 2021 RNA Therapeutics Symposium. Information on how to register and awards we have available can be found here: umassmed.edu/RNATx/register/. #RNATx2021

Hi everyone! The Zamore lab is looking to hire a new lab manager. If you know of anyone who might be interested, please send them my way. Our posting can be found here: hhmi.wd1.myworkdayjobs.com/en-US/External…

We're pleased to announce today $195,000 in #SeedFund awards to 13 MA faculty researchers through our Acorn Innovation program! Research addresses #breastcancer #kidneydisease, #foodwaste, #pfas #lithiumionbatteries and more. Read about the awardees here: mass-ventures.com/massventures-a…

Thanks to Acorn Innovation program for award funding critical experiments to de-risk our miRNA technology!

With gratitude for the transformational philanthropy of the Morningside Foundation, UMass Medical School is now UMass Chan Medical School. Learn about the history-making gift at University of Massachusetts and the name changes for #UMassChan's three schools: bit.ly/3h9673u #WhyUMassChan

Unlocked and open to all readers: UMass Medical School will be renamed following a $175M donation from the Chan family's Morningside Foundation. bizjournals.com/boston/news/20… via Boston Business Journal

Chancellor Michael F. Collins says a $175 million gift from the Morningside Foundation will permit UMass Chan Medical School to recruit renowned faculty, conduct more breakthrough biomedical research & offer financial support to highly qualified students: bit.ly/2X00c9x

📢 LIVESTREAM ALERT: Go to umassmed.edu at 10 a.m. to watch a news conference on UMass Medical School's new name and the endowment fund that's been created to hold the $175 million gift from the Morningside Foundation: bit.ly/3mR2EKG #UMassChan

In the animal germline, piRNAs silence transposons and regulate host genes. Without piRNAs, animals are sterile. If you want to learn how animals protect and destroy piRNAs, read the latest paper from the Zamore lab. With Cansu Colpan ZamoreLabUMass. cell.com/molecular-cell…

Very happy to start this account with a great news - our new proximity biotinylation technology for genetically unmodified cells is published in Molecular Cell! Here is the link: bit.ly/3COnM9t

The Wu lab is looking for motivated PhD students to study the paternal effects of #smallRNA in embryo development at the Faculty of Medicine UNIGE_en. A sincere thank you to PRIMA Swiss National Science Foundation for funding this exciting project! If interested, please DM or email me.

Relaxed targeting rules allow PIWI-clade Argonaute proteins to silence ever-mutating transposons. Our data overturn the common presumption that AGO and PIWI Argonautes follow similar rules for identifying their RNA targets. biorxiv.org/content/10.110…

New manuscript from Zamore lab explains the biological advantage of PIWI proteins and piRNAs over AGOs as defense against transposons.

Relaxed targeting rules allow PIWI-clade Argonaute proteins to silence ever-mutating transposons biorxiv.org/content/10.110…

Peiwei Chen and I were happy to contribute to this remarkable work from Yukiko M. Yamashita and ZamoreLabUMass. I am fond of the Stellate piRNA repression system as it was the topic of my PhD work a long time ago. A short explanation of new results 🧵 biorxiv.org/cgi/content/sh…

How do Dicer-1 and Loqs-PB make miRNA? We captured 6 cryo-EM structures showing stages of pre-miRNA cleavage. Dicer•Loqs bend pre-miRNA to cleave the right targets: cell.com/molecular-cell… Fun collab. with ZamoreLabUMass and Traci Hall (NIEHS). Congrats,Karina Jouravleva and Dima!

Congratulations, Dr. Yongjin Lee! Great job! Your artistically unique view of your favorite model organism is amazing.