Excited to see our paper published in Nature Communications Nature Communications! We showed the evidence that disruption of tumor stroma first e.g., using FAPCAR T cells, can render the tumor respond to subsequent TAA immunotherapy! #stroma #CAR T cell

#ICYMI: Read the commentary— Bursting Tumor Bubbles to Improve #CARTcell Therapy, by Ortiz-Espinosa and Shivani Srivastava. aacrjournals.org/cancerres/arti… Fred Hutch Cancer Center

Our collaboration with Drs. Zhong and Guo. We showed that extracellular vehicles can inhibit the function of CAR T cells!

That is AMAZING!

In a Review now published online, Steven Albelda provides an overview of what we know so far about CAR T cell therapies for solid tumours and proposes strategies to improve outcomes: nature.com/articles/s4157…

#REVIEW 🚨 Fibroinflammation contributes to tumour initiation, growth and metastasis. Zebin Xiao & Ellen Puré outline the complexity of cancer-associated fibroinflammation and provide insights on therapeutically targeting this. Penn 👀 ⬇️ bit.ly/4iP3PnV

It’s an honor to have our review on cancer-associated fibroinflammation published in Nature Reviews Cancer . We’re excited to continue exploring this area and look forward to sharing our next findings on this important question!