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Wow! Huxley’s first ever letter to Osmond, 1953, before the former’s “mescaline/doors of perception” trip and the latter’s coining of “psychedelic” (1956): and he refers to “canalization”! Amazing! pubmed.ncbi.nlm.nih.gov/36584883/

A subset of neurons in the medial prefrontal cortex is shown to exert top-down regulation of adaptive innate reproductive behaviors by integrating social cues with estrous states to orchestrate sociosexual behaviors cell.com/cell/fulltext/… Cell

Enlightenment consciously chosen means to relinquish your attachment to past and future and to make the Now the main focus of your life. It means choosing to dwell in the state of presence rather than in time. It means saying yes to what is.

Misfit power ✊ Enjoy a moment from the Dead’s appearance on Tom Snyder’s ‘Tomorrow Show’ during their ‘Reckoning’ press tour 44 years ago this month.

View from the garden today

linkedin.com/posts/fiona-h-…

We are excited to announce the launch of The Enamine Scientific Research Institute (Enamine SRI). The new Institute, a non-profit organization, aims to coordinate scientists in Ukraine supporting research and innovations in chemistry, biology, computer science, and early-stage

NIH Extends the ESI eligibility window drugmonkey.wordpress.com/2025/05/21/nih… via Drug Monkey

Michael Eisen Do you have any pertinent examples? I’m struck by how often you make these sorts of pronouncements (as if you were Moses bringing down the tablets) without providing evidence.

🚨 HB 3717/SB 2308 is moving forward! This bill marks the largest state-funded psychedelic research initiative in U.S. history—a bold, necessary step toward confronting one of the most urgent health crises of our time: the veteran suicide epidemic. At VETS, we’ve been proud to

10.03 billion ready-to-dock 3D lead-like molecules in biologically relevant forms are now freely available for your ligand discovery projects. zinc22.docking.org.

Happy to announce that two papers from the group appeared in press today – one in Nature Communications and the other in Neuron , links below. The first introduces a bioresorbable, wireless electrical stimulator to accelerate healing of damaged peripheral nerves – a temporary

You are not alone in this NIH grant game drugmonkey.wordpress.com/2025/05/21/you… via Drug Monkey

Japanese people 1.

PTSD patients who failed prolonged exposure (N=9) had VNS turned on only during PE-> all 9 patients in remission post-treatment. brainstimjrnl.com/article/S1935-…

Could both be true?

1967 article by Kast Attenuation of anticipation: A therapeutic use of lysergic acid diethylamide link.springer.com/article/10.100…

Sad to hear Amanda Feilding, the Queen of Consciousness, passed. Her gran knew Huxley & Nietzsche. Her interest in trepanning led her to drill a hole in her own head. I interviewed her once. All my life, I’ve wanted to hang around with people like her. filtermag.org/queen-consciou…